Infection Biology Unit, German Primate Center, Kellnerweg 4, 37077 Göttingen, Germany.
Cell Host Microbe. 2011 Jul 21;10(1):5-7. doi: 10.1016/j.chom.2011.07.003.
Lozach and colleagues show that phleboviruses (bunyaviridae), which comprise important emerging viral pathogens, exploit the C-type lectin DC-SIGN for dendritic cell binding, entry, and infection. The authors elegantly visualize the cellular processes underlying DC-SIGN-dependent viral capture and uptake.
洛扎赫及其同事表明，弹状病毒科（布尼亚病毒科）中的噬血细胞性淋巴组织细胞增多症病毒是重要的新兴病毒病原体，利用 C 型凝集素 DC-SIGN 结合树突状细胞、进入并感染细胞。作者巧妙地观察到了 DC-SIGN 依赖性病毒捕获和摄取的细胞过程。
