Université de la Méditerranée, URMITE UMR 6236, CNRS-IRD, Faculté de Médecine et de Pharmacie, 27 Bd Jean Moulin, 13385 Marseille cedex 05, France.
Int J Infect Dis. 2011 Oct;15(10):e710-5. doi: 10.1016/j.ijid.2011.05.017. Epub 2011 Jul 20.
The aim of this study was to examine the mechanisms by which weather conditions, the incidence of Leptospira in reservoir populations, and various socio-ecological factors are driving the emergence of leptospirosis in Marseille, France.
Over the last 30 years our laboratory has surveyed all human cases of leptospirosis in Marseille using clinical, epidemiological, serological, and molecular tools. Data for the weather conditions in Marseille were collected from the official meteorological station, and garbage management strikes were monitored through the local press. Rats were trapped in alleys near to where the patients may have acquired leptospirosis.
Three new cases of autochthonous leptospirosis are reported. The global tendency for rainfall showed a slight increase over the period under analysis. The index case of leptospirosis occurred after a heavy rainfall with flooding. Over the last 10 years Marseille has undergone 82 days of garbage management strikes. Leptospira DNA was detected in two of 11 rats.
The emergence of leptospirosis has become a public health problem in Marseille, and is associated with a combination of heavy rainfall and garbage collection strikes in which garbage is left on the street and thereby contributes to the expansion of the rat population on the surface.
本研究旨在探讨天气条件、储水种群中钩端螺旋体的发病率以及各种社会生态因素是如何导致法国马赛钩端螺旋体病的出现。
在过去的 30 年中，我们的实验室使用临床、流行病学、血清学和分子工具调查了马赛所有的人类钩端螺旋体病病例。马赛的天气条件数据是从官方气象站收集的，垃圾管理罢工是通过当地媒体监测的。在可能感染钩端螺旋体病的患者附近的小巷里，我们用捕鼠器捕获老鼠。
报告了三例新的本地钩端螺旋体病病例。分析期间，总降雨量呈轻微上升趋势。首例钩端螺旋体病发生在一场大雨和洪水之后。在过去的 10 年中，马赛经历了 82 天的垃圾管理罢工。在 11 只老鼠中，有 2 只检测到了钩端螺旋体 DNA。
钩端螺旋体病的出现已成为马赛的一个公共卫生问题，与大雨和垃圾收集罢工有关，垃圾收集罢工期间垃圾留在街上，从而导致地面上老鼠种群的扩大。
