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大麻动脉炎:文献复习。

Cannabis arteritis: review of the literature.

机构信息

From the Departments of Addictology (OC, MG) and Internal Medicine (ML), University Hospital of Lille, Lille; and Department of Addictology (LK, CA, A Benyamina, A Boissonas), Paul Brousse University Hospital, Villejuif, France.

出版信息

J Addict Med. 2010 Dec;4(4):191-6. doi: 10.1097/ADM.0b013e3181beb022.

Abstract

Consumption of cannabis in young adults has continued to increase in recent years. Cannabis arteritis was first described in the 1960s, but the number of cases has continued to increase. We reviewed current knowledge of the different types of cannabis arteritis in young adults and found 70 cases of cannabis arteritis in the literature. We discuss physiopathological arguments in favor of cannabis vascular toxicity per se, although we did not find sufficient evidence to identify cannabis arteritis as a specific diagnostic entity. Many factors suggest a link between cannabis consumption and arteritis in young adults, but it is difficult to say whether this type of arteritis is similar to thromboangiitis obliterans. We were unable to demonstrate a formal association between cannabis smoking and the development of thromboangiitis obliterans, because most case reports showed associated tobacco smoking (97%) and the number of years cannabis had been smoked by the participants was mostly unknown. Cannabis consumption would however seems to be an aggravating factor, together with tobacco, in arteritis, which occurs in young adults.

摘要

近年来,年轻人吸食大麻的现象持续增加。20 世纪 60 年代首次描述了大麻性动脉炎,但病例数量持续增加。我们回顾了目前关于年轻人不同类型大麻性动脉炎的知识,并在文献中发现了 70 例大麻性动脉炎。我们讨论了支持大麻血管毒性本身的生理病理论点,尽管我们没有找到足够的证据将大麻性动脉炎确定为一种特定的诊断实体。许多因素表明大麻的使用与年轻人的动脉炎之间存在关联,但很难说这种类型的动脉炎是否与血栓闭塞性脉管炎相似。我们无法证明大麻吸烟与血栓闭塞性脉管炎的发展之间存在正式关联,因为大多数病例报告显示存在烟草吸烟(97%),而且大多数参与者吸食大麻的年限也不得而知。大麻的使用似乎与烟草一起成为了年轻人动脉炎的加重因素。

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