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巴西人群颌骨动脉瘤样骨囊肿九例的临床病理分析。

Clinical pathological analysis of nine cases of aneurysmal bone cyst of the jaws in a Brazilian population.

机构信息

Department of Dentistry, Federal University of Rio Grande do Norte, Avenida Senador Salgado Filho, 1787-Lagoa Nova, Natal, RN, CEP 59056-000, Brazil.

出版信息

Eur Arch Otorhinolaryngol. 2012 Mar;269(3):971-6. doi: 10.1007/s00405-011-1705-9. Epub 2011 Jul 19.

DOI:10.1007/s00405-011-1705-9
PMID:21769447
Abstract

Aneurysmal bone cysts (ABCs) are benign osteolytic lesions that occur rarely in the jaws. The aim of this study was to investigate the clinical, radiographical and pathological features of ABCs of the jaws. A retrospective analysis of the content of a 39-year database, including nine cases of ABCs of the jaws diagnosed from the archives of the Oral Pathology Service. Nine patients (3 males and 6 females), ranging in age from 5 to 33 years were included. Seven (7/9) lesions were located in the mandible and two (2/9) in the maxilla. A painful swelling was the most common clinical finding (n = 4, 4/9). Radiologically, the lesions frequently presented as multilocular (5/9), well defined (4/9), bone expansion and perforation (2/9). Pathological analysis revealed that two cases were associated with central ossifying fibroma and one case with central giant cell lesion. Histomorphology showed a predominance of the solid type (5/9) and of sinusoidal pseudocystic spaces (4/9). Giant cells, osteoid material, calcified material, blood vessels and hemosiderin deposits were observed in 6/9, 7/9, 8/9, 9/9 and 7/9, respectively. The patients with ABCs presented clinical and radiographical features, which often posed a diagnostic dilemma. Knowledge about the most common characteristics of ABCs may contribute to the establishment of a more accurate diagnosis.

摘要

骨巨细胞瘤(ABC)是一种罕见的发生在颌骨的良性溶骨性病变。本研究旨在研究颌骨 ABC 的临床、影像学和病理学特征。对口腔病理科档案中诊断为颌骨 ABC 的 9 例病例的 39 年数据库内容进行回顾性分析。纳入 9 例患者(男 3 例,女 6 例),年龄 5 至 33 岁。7 例(7/9)病变位于下颌骨,2 例(2/9)位于上颌骨。最常见的临床表现为疼痛性肿胀(n=4,4/9)。影像学上,病变常呈多房性(5/9),边界清楚(4/9),伴有骨膨胀和穿孔(2/9)。病理分析显示,2 例与中央骨化性纤维瘤相关,1 例与中央巨细胞瘤相关。组织形态学显示,实性型(5/9)和窦状假囊型(4/9)多见。6/9、7/9、8/9、9/9 和 7/9 例分别观察到巨细胞、类骨质物质、钙化物质、血管和含铁血黄素沉积。ABC 患者表现出的临床和影像学特征常常带来诊断上的困难。了解 ABC 最常见的特征可能有助于建立更准确的诊断。

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