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[肝脏的现代CT及PET/CT成像]

[Modern CT and PET/CT imaging of the liver].

作者信息

Klasen J, Heusner T A, Riegger C, Reichelt D, Kuhlemann J, Antoch G, Blondin D

机构信息

Institut für Diagnostische und Interventionelle Radiologie, Medizinische Fakultät, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Deutschland.

出版信息

Radiologe. 2011 Aug;51(8):671-9. doi: 10.1007/s00117-010-2125-3.

DOI:10.1007/s00117-010-2125-3
PMID:21769701
Abstract

Computed tomography (CT) is now widely available and represents an important and rapid method for the diagnostics of acute liver disease, characterization of focal liver lesions, planning of interventional therapy measures and postintervention control. In recent years CT has not become less important despite the increasing value of magnetic resonance imaging (MRI). By the use of different contrast medium phases good characterization of space-occupying lesions can be achieved. For the diagnostics of hepatocellular carcinoma (HCC) a triphasic examination protocol should always be implemented. The introduction of dual energy CT increased the sensitivity of imaging of hypervascularized and hypovascularized liver lesions and by the use of virtual native imaging it has become possible to avoid additional native imaging which reduces the x-ray exposition of patients. Positron emission tomography (PET) has an advantage for imaging in oncology because nearly the complete body of the patient can be screened and this is the main indication for PET/CT (whole-body staging). For purely hepatic problems 18F-fluorodeoxyglucose (FDG)-PET/CT using diagnostic CT data has a higher precision than CT alone but is inferior to MRI.

摘要

计算机断层扫描(CT)如今已广泛应用,是诊断急性肝病、鉴别肝脏局灶性病变、规划介入治疗措施及进行干预后复查的重要且快速的方法。近年来,尽管磁共振成像(MRI)的价值不断提升,但CT的重要性并未降低。通过使用不同的造影剂期相,可很好地鉴别占位性病变。对于肝细胞癌(HCC)的诊断,应始终采用三相检查方案。双能CT的引入提高了对肝脏富血供和乏血供病变成像的敏感性,并且通过使用虚拟平扫成像,得以避免额外的平扫成像,从而减少了患者的X线照射。正电子发射断层扫描(PET)在肿瘤成像方面具有优势,因为几乎可以对患者的整个身体进行筛查,这也是PET/CT(全身分期)的主要适应证。对于单纯的肝脏问题,使用诊断CT数据的18F-氟脱氧葡萄糖(FDG)-PET/CT比单纯CT具有更高的精度,但不如MRI。

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Evaluation of metabolic characteristics and viability of lipiodolized hepatocellular carcinomas using 18F-FDG PET/CT.使用 18F-FDG PET/CT 评估碘油化疗栓塞肝癌的代谢特征和活力。
J Nucl Med. 2010 Dec;51(12):1849-56. doi: 10.2967/jnumed.110.079244.
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Detection of hepatocellular carcinoma with PET/CT: a prospective comparison of 18F-fluorocholine and 18F-FDG in patients with cirrhosis or chronic liver disease.正电子发射断层扫描/计算机断层扫描(PET/CT)探测肝细胞癌:肝硬化或慢性肝病患者氟代胆碱 18F 和氟代脱氧葡萄糖 18F-FDG 的前瞻性比较。
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双能 CT 与多排 CT 再探:原理与临床应用综述。
Diagn Interv Radiol. 2011 Sep;17(3):181-94. doi: 10.4261/1305-3825.DIR.3860-10.0. Epub 2010 Nov 14.
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Dual-energy-CT of hypervascular liver lesions in patients with HCC: investigation of image quality and sensitivity.肝细胞癌患者富血管性肝病变的双能 CT 研究:图像质量和敏感性评估。
Eur Radiol. 2011 Apr;21(4):738-43. doi: 10.1007/s00330-010-1964-7. Epub 2010 Oct 10.
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Whole-body F-18-fluoro-2-deoxyglucose positron emission tomography/computed tomography imaging in the follow-up of metastatic uveal melanoma.全身 F-18-氟代-2-脱氧葡萄糖正电子发射断层扫描/计算机断层扫描成像在转移性葡萄膜黑色素瘤随访中的应用。
Melanoma Res. 2010 Dec;20(6):511-6. doi: 10.1097/CMR.0b013e3283403d6c.
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Added value of 80 kVp images to averaged 120 kVp images in the detection of hepatocellular carcinomas in liver transplantation candidates using dual-source dual-energy MDCT: results of JAFROC analysis.双源双能 MDCT 平扫 120kVp 平均图像加用 80kVp 图像对肝移植候选者肝细胞癌检测的附加价值:JAFROC 分析结果。
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Diagnostic imaging of colorectal liver metastases with CT, MR imaging, FDG PET, and/or FDG PET/CT: a meta-analysis of prospective studies including patients who have not previously undergone treatment.结直肠癌肝转移的 CT、MR 成像、FDG PET 和/或 FDG PET/CT 诊断影像学:一项包括未经治疗患者的前瞻性研究的荟萃分析。
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Dual-energy multidetector CT: how does it work, what can it tell us, and when can we use it in abdominopelvic imaging?双能多排 CT:它是如何工作的,它能告诉我们什么,以及何时可以在腹部和盆腔成像中使用它?
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