Department of Dermatology, The General Infirmary at Leeds, Leeds, UK.
Clin Exp Dermatol. 2011 Aug;36(6):621-3. doi: 10.1111/j.1365-2230.2010.04004.x.
Acquired port-wine stains (PWSs) are rare but well recognized, and have often been reported in association with localized trauma. Various drugs have also been implicated as aetiological factors. We report the case of a 71-year-old man with an extensive congenital PWS affecting the left side of the face, upper chest and upper back. At the age of 69 years, he began to develop similar areas on his right hand and forearm, left hand and left knee. This corresponded temporally to being started on simvastatin and metformin, both of which may promote angiogenesis.
获得性葡萄酒色斑(PWS)罕见但特征明显,常与局部创伤相关报道。多种药物也被认为是病因。我们报告了一例 71 岁男性患者,其左侧面部、胸上部和上背部存在广泛先天性 PWS。69 岁时,他开始在右手和前臂、左手和左膝出现类似区域。这与他开始使用辛伐他汀和二甲双胍的时间相对应,这两种药物都可能促进血管生成。