各种增溶剂对牛肾上腺皮质质膜中血管紧张素II受体的影响。
Effect of various solubilizers on angiotensinII receptors in bovine adrenocortical plasma membranes.
作者信息
Forget G, Heisler S
出版信息
Experientia. 1979 Jan 15;35(1):125-6. doi: 10.1007/BF01917918.
PMID:217711
Abstract
3 nonionic detergents, Triton X-100, Lubrol WX and NP-40, inhibited binding of [3H]-ATII to bovine adrenocortical plasma membranes. This effect appeared to be direct and not due to solubilization of the ATII receptor by these agents. Sodium deoxycholate and the chaotropic ions, ClO4- and Br-, produced effects similar to the nonionic detergents.
摘要
三种非离子去污剂，即曲拉通X-100、卢博罗尔WX和NP-40，抑制了[3H]-血管紧张素II与牛肾上腺皮质质膜的结合。这种作用似乎是直接的，并非由于这些试剂使血管紧张素II受体溶解所致。脱氧胆酸钠以及离液序列高的离子ClO4-和Br-产生了与非离子去污剂类似的作用。
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