Natural Products Chemistry Division, North East Institute of Science & Technology, CSIR, Jorhat 785 006, India.
Steroids. 2011 Nov;76(12):1341-5. doi: 10.1016/j.steroids.2011.06.014. Epub 2011 Jul 13.
Microwave (MW) assisted reactions are currently having considerable importance in the synthesis of organic compounds. Considering the remarkable application of Baeyer-Villiger (BV) reaction in the synthesis of natural products and steroid-peptide conjugates, we report here some of our findings of BV oxidation of carbonyl compounds with special reference to steroidal ketones under MW irradiation justifying its accelerating effect.
微波辅助反应在有机化合物的合成中目前具有相当重要的地位。鉴于 Baeyer-Villiger（BV）反应在天然产物和甾体-肽缀合物合成中的显著应用，我们在此报告了一些我们在微波照射下对羰基化合物进行 BV 氧化的发现，特别是对甾体酮的氧化，证明了其加速效应。
