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海湾地区房颤事件调查(Gulf SAFE):阿拉伯中东地区房颤患者的设计与基线特征

Gulf Survey of Atrial Fibrillation Events (Gulf SAFE): design and baseline characteristics of patients with atrial fibrillation in the Arab Middle East.

作者信息

Zubaid Mohammad, Rashed Wafa A, Alsheikh-Ali Alawi A, Almahmeed Wael, Shehab Abdullah, Sulaiman Kadhim, Al-Zakwani Ibrahim, Alqudaimi Ahmed, Asaad Nidal, Amin Haitham

机构信息

Department of Medicine, Faculty of Medicine, Kuwait University, Safat, Kuwait.

出版信息

Circ Cardiovasc Qual Outcomes. 2011 Jul;4(4):477-82. doi: 10.1161/CIRCOUTCOMES.110.959700.

DOI:10.1161/CIRCOUTCOMES.110.959700
PMID:21772004
Abstract

BACKGROUND

Atrial fibrillation (AF) is the most common serious cardiac arrhythmia, and its prevalence is expected to increase. There is lack of data about patient characteristics, practice patterns, and outcomes of AF in the Arab Middle East.

METHODS AND RESULTS

The Gulf Survey of Atrial Fibrillation Events (Gulf SAFE) is a prospective, observational registry of patients with AF with a 12-month follow-up. The registry was emergency room based. Between October 2009 and June 2010, 2043 consecutive patients with AF were enrolled from 23 hospitals in 6 Middle Eastern Gulf countries. Data were collected on a standardized case report form and entered online. Data collected included patient demographics, medical history, type of AF, treatment, and outcome of emergency room visit. If patients were admitted, details of their treatment, investigations, and outcomes during hospital stay were collected. Completion of 12-month follow-up is expected by July 2011. The mean age was 57 years, and 52% were men. The most common concomitant condition was hypertension, present in 1072 (52%) patients. At enrollment, 28% of patients had a history of coronary artery disease, 30% had diabetes, and 16% had rheumatic valve disease. History of stroke and transient ischemic attacks were reported in 9% and 4% of patients, respectively. The most common type of AF, first attack AF, occurred in 37%, whereas 19% of patients had lone AF.

CONCLUSIONS

Gulf SAFE will provide valuable insights into AF management and outcomes in the Gulf region of the Middle East.

摘要

背景

心房颤动(AF)是最常见的严重心律失常,其患病率预计将会上升。在阿拉伯中东地区,缺乏关于房颤患者特征、治疗模式及治疗结果的数据。

方法与结果

海湾地区心房颤动事件调查(Gulf SAFE)是一项针对房颤患者的前瞻性观察性登记研究,随访期为12个月。该登记研究以急诊室为基础。在2009年10月至2010年6月期间,从6个中东海湾国家的23家医院连续纳入了2043例房颤患者。数据通过标准化病例报告表收集并在线录入。收集的数据包括患者人口统计学信息、病史、房颤类型、治疗情况以及急诊室就诊结果。如果患者入院,则收集其住院期间的治疗、检查及结果详情。预计到2011年7月完成12个月的随访。平均年龄为57岁,男性占52%。最常见的合并症是高血压,1072例(52%)患者患有高血压。入组时,28%的患者有冠状动脉疾病史,30%有糖尿病史,16%有风湿性瓣膜病。分别有9%和4%的患者报告有中风和短暂性脑缺血发作史。最常见的房颤类型是初发性房颤,占37%,而19%的患者为孤立性房颤。

结论

海湾地区心房颤动事件调查(Gulf SAFE)将为中东海湾地区房颤的管理及治疗结果提供有价值的见解。

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