Lenyoun E Hanson, Lampert Joshua A, Xipoleas George D, Taub Peter J
Mount Sinai School of Medicine, Kravis Children's Hospital, New York, New York, USA.
J Craniofac Surg. 2011 Jul;22(4):1378-82. doi: 10.1097/SCS.0b013e31821cc26d.
Frontonasal dysplasia is a severe malformation composed of cranial, ophthalmic, nasal, upper lip, and palatal deformities. Reconstruction in these patients requires complex craniofacial efforts. A 19-year-old woman with frontonasal dysplasia was treated at our institution where she had undergone multiple prior reconstructive surgeries including facial bipartition and cantilevered calvarial bone graft for nasal reconstruction. She later presented with a palpable bone graft prominence, associated contour deformity, and an area of overlying paper-thin skin at the nasal tip. Although there was no ulceration, the threat of graft extrusion required immediate attention. The prominent bone graft tip was debrided, and the overlying soft tissue envelope was augmented using acellular dermal matrix. No surgical complication was encountered. The patient had successful salvage of the bone graft and a pleasing aesthetic outcome at 9 months of follow-up. The use of acellular dermal matrix has proven to be beneficial in the correction of nasal contour deformities given its soft, natural appearance, availability, affordability, and safety. Its use also avoids further donor site morbidity. We suggest acellular dermal matrix as a graft material in revision rhinoplasties for cases of acquired nasal contour deformity and threatened bone graft extrusion. This is the first report known to the authors using acellular dermal matrix during staged nasal reconstruction in a patient experiencing frontonasal dysplasia.
额鼻发育异常是一种严重的畸形,由颅骨、眼部、鼻部、上唇和腭部畸形组成。对这些患者进行重建需要复杂的颅面手术。一名19岁的额鼻发育异常女性在我们机构接受治疗,她此前已经接受了多次重建手术,包括面部二分法和用于鼻重建的悬臂颅骨骨移植。她后来出现了可触及的骨移植突出、相关的轮廓畸形以及鼻尖处覆盖的薄如纸的皮肤区域。尽管没有溃疡,但骨移植挤出的风险需要立即关注。突出的骨移植尖端被清创,覆盖的软组织包膜使用脱细胞真皮基质进行了增厚。未遇到手术并发症。患者成功挽救了骨移植,在随访9个月时获得了满意的美学效果。鉴于脱细胞真皮基质柔软、自然的外观、可用性、可承受性和安全性,其已被证明在矫正鼻轮廓畸形方面是有益的。其使用还避免了进一步的供区并发症。对于获得性鼻轮廓畸形和有骨移植挤出风险的病例,我们建议在鼻整形修复术中使用脱细胞真皮基质作为移植材料。这是作者所知的第一例在额鼻发育异常患者的分期鼻重建中使用脱细胞真皮基质的报告。