Hicks Gómez J J
División de Biologia de la Reproducción, Unidad de Investigación Biomédica, CMN, IMSS, México, D.F.
Ginecol Obstet Mex. 1990 Apr-May;58 Suppl 1:47-52.
In order for implantation to occur, the endometrium must be adequately differentiated, a estate which results from the sequential interaction of progesterone and estrogens, and the local effects of prostaglandins and histamine. Nevertheless, the exact mechanism through which these hormones affect the uterus is not clearly understood. Recently it has been proposed the role of second messengers (cAMP.cGMP, inositol triphosphate and diacylglycerol) in this process. All these messengers are related with the intracellular mechanisms of proteic and steroid hormones action.
为了实现着床，子宫内膜必须充分分化，这一状态是由孕激素和雌激素的顺序相互作用以及前列腺素和组胺的局部作用所导致的。然而，这些激素影响子宫的确切机制尚不清楚。最近有人提出第二信使（环磷酸腺苷、环磷酸鸟苷、肌醇三磷酸和二酰基甘油）在这一过程中的作用。所有这些信使都与蛋白质和类固醇激素作用的细胞内机制有关。
