Lin W, Zhang Z
E.N.T. Department of Combined TCM and Western Medicine, Tianjin.
J Tradit Chin Med. 1990 Dec;10(4):267-73.
From clinical practice, the authors concluded that the principal pathogenic factor in allergic rhinitis is deficient resistance of the body surface, and the patient is exposed to invasion of wind-evil. 495 cases of the allergic rhinitis have been treated with the method of invigorating vital energy and strengthening the body surface resistance (Bu Qi Gu Biao); the total effective rate was 84%, and the recurrence rate was 13.2% in a follow-up of 2 years. The changes in plasma cyclic nucleotides of the patients, and the ultrastructure of nasal mucosa of patients and animal models were also observed before and after treatment. The results showed that the TCM therapy tended to normalize the plasma cyclic nucleotide level, to improve the morphology and function of cells and organelles, to restore the function of mucosal cilia, to reduce the infiltration of eosinophils and their degranulation, to reduce tissue edema, and to eliminate the deposit of immune complexes.
从临床实践来看，作者得出结论：过敏性鼻炎的主要致病因素是体表抵抗力不足，患者易受风邪侵袭。采用益气固表法治疗过敏性鼻炎495例，总有效率为84%，随访2年复发率为13.2%。同时观察了患者血浆环核苷酸的变化以及治疗前后患者和动物模型鼻黏膜的超微结构。结果显示，中医治疗倾向于使血浆环核苷酸水平恢复正常，改善细胞和细胞器的形态及功能，恢复黏膜纤毛功能，减少嗜酸性粒细胞浸润及其脱颗粒，减轻组织水肿，并消除免疫复合物沉积。
