促肾上腺皮质激素和地塞米松抑制试验在抑郁症中的应用。
Acth and the dexamethasone suppression test in depression.
机构信息
Senior Resident, Department of Psychiatry, K.G's Medical College, Lucknow.
出版信息
Indian J Psychiatry. 1992 Jan;34(1):53-4.
Abstract
Hypercortisolemia, as measured by baseline serum Cortisol levels (Carroll and Mendels, 1976) and abnormal response to dexamethasone suppression test (DST) (Carroll et at., 1981) is thought to characterize abnormal hypothalamic-pituitory- adrenal (HPA) axis functions in patients of depression. Whether adrenocorticotrophic hormone (ACTH) shows similar abnormalities is a matter of controversy. Whereas Nasretal. (1983) and Roy et al. (1986) reported higher plasme ACTH levels in depressed patients as compared to controls. Fang et al. (1981) and Yerevanian and Woolf (1933) did not find such difference.
摘要
库欣血症，如通过基础血清皮质醇水平（Carroll 和 Mendels，1976）和对地塞米松抑制试验（DST）的异常反应（Carroll 等人，1981）来衡量，被认为是抑郁症患者下丘脑-垂体-肾上腺（HPA）轴功能异常的特征。促肾上腺皮质激素（ACTH）是否表现出类似的异常是一个有争议的问题。虽然 Nasretal.（1983）和 Roy 等人（1986）报道与对照组相比，抑郁患者的血浆 ACTH 水平较高，但 Fang 等人（1981）和 Yerevanian 和 Woolf（1933）并没有发现这种差异。
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