抑郁症患者和正常对照者在服用地塞米松前后的血浆促肾上腺皮质激素（ACTH）水平。
Pre- and post-dexamethasone plasma ACTH levels in depressed patients and normal controls.
作者信息
Roy A, Gold P, Pickar D, Wolkowitz O M, Chrousos G, Paul S M
出版信息
J Affect Disord. 1986 Mar-Apr;10(2):95-9. doi: 10.1016/0165-0327(86)90032-7.
PMID:3013965
Abstract
Levels of plasma ACTH in relation to dexamethasone administration were evaluated in 16 medication-free patients with a major depressive episode and 39 normal controls. Depressed patients had significantly higher levels of plasma ACTH than controls both at 4:00 p.m. predexamethasone and 4:00 p.m. postdexamethasone. The significance of this finding is discussed.
摘要
在16例无药物治疗的重度抑郁发作患者和39名正常对照者中，评估了与地塞米松给药相关的血浆促肾上腺皮质激素（ACTH）水平。抑郁患者在下午4点（地塞米松给药前）和下午4点（地塞米松给药后）的血浆ACTH水平均显著高于对照组。讨论了这一发现的意义。
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