脑皮层发育畸形的术中超声。
Intraoperative ultrasound in malformations of cortical development.
机构信息
Klinik für Neurochirurgie, Universitätsklinikum Essen, Essen, Germany.
出版信息
Ultraschall Med. 2011 Dec;32 Suppl 2:E69-74. doi: 10.1055/s-0031-1273490. Epub 2011 Jul 20.
PURPOSE
Malformations of cortical development (MCD) are a common cause of medically refractory focal epilepsy. However, the intraoperative definition of MCD can be challenging. In this study we assess the feasibility of intraoperative ultrasound (IOUS) for the intraoperative localization of MCD.
MATERIALS AND METHODS
Five epilepsy patients with at least one suspected lesion of MCD were operated with the aid of IOUS. IOUS was compared to preoperative MRI and histopathology.
RESULTS
In three cases of focal cortical dysplasia (FCD) type IIB and one case of periventricular heterotopia, the lesions could be delineated well on IOUS and the configuration of the lesion corresponded to the appearance on MRI. However, only one of two FCD type I lesions could be detected on IOUS.
CONCLUSION
IOUS can be helpful in defining FCD IIB as well as periventricular heterotopia intraoperatively, but this seems to be more difficult in FCD type I.
目的
皮质发育畸形（MCD）是药物难治性局灶性癫痫的常见原因。然而，MCD 的术中定义具有一定挑战性。本研究旨在评估术中超声（IOUS）用于 MCD 术中定位的可行性。
材料与方法
5 例至少有 1 个疑似 MCD 病变的癫痫患者在 IOUS 辅助下进行手术。将 IOUS 与术前 MRI 和组织病理学进行比较。
结果
在 3 例 IIB 型局灶性皮质发育不良（FCD）和 1 例脑室周围异位症病例中，IOUS 能够很好地区分病变，病变的形态与 MRI 上的表现一致。然而，2 例 FCD Ⅰ型病变中只有 1 例可在 IOUS 上检测到。
结论
IOUS 有助于术中明确 FCD IIB 和脑室周围异位症，但在 FCD Ⅰ型中似乎更难检测到。
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