Holthausen Hans, Pieper Tom, Winkler Peter, Bluemcke Ingmar, Kudernatsch Manfred
Neuropediatric Clinic and Clinic for Neurorehabilitation, Epilepsy Center for Children and Adolescents, Schoen-Klinik Vogtareuth, Krankenhausstr. 20, D - 83569, Vogtareuth, Germany,
Childs Nerv Syst. 2014 Dec;30(12):2015-26. doi: 10.1007/s00381-014-2549-6. Epub 2014 Sep 27.
The prevalence of focal cortical dysplasia (FCD) in pediatric patients with focal epilepsy is not exactly known because authors of publications in which the etiologies of epilepsies are listed, but which are not dealing specifically with epilepsy surgery issues, tend to lump together the many kinds of malformations of cortical development (MCD), of which FCDs, because of their relative frequency, are the most relevant subtypes. Out of 561 patients with MCD (children and adults) operated at centers in Europe who do feed data into the "European Epilepsy Brain Bank," 426 (76 %) had FCD.
局灶性皮质发育异常(FCD)在患有局灶性癫痫的儿科患者中的患病率尚不完全清楚,因为在列出癫痫病因但未专门涉及癫痫手术问题的出版物中,作者往往将多种皮质发育畸形(MCD)归为一类,其中FCD由于相对常见,是最相关的亚型。在欧洲各中心接受手术的561例MCD患者(儿童和成人)中,有426例(76%)患有FCD,这些患者的数据被录入了“欧洲癫痫脑库”。