Boston University Medical Center, Boston, Massachusetts 02118, USA.
Med Phys. 2011 May;38(5):2595-601. doi: 10.1118/1.3582701.
Recently, a fast-kVp switching (FKS) dual-energy method has been presented with clinical and phantom results to demonstrate its efficacy. Patient dose concern has been raised on FKS dual-energy since it involves higher energy acquisition at 140 kVp and slower gantry rotation time (e.g., 0.9-1 s) as opposed to 0.5 s as used in routine single-energy exams. The purpose of our study was to quantitatively compare the CTDI(VOL) of FKS and routine CT exams under the body and head conditions.
For a fair comparison, we have to overcome the difficulty of unmatched protocols between FKS and routine CT exams. In this paper, we propose to match the low contrast detectability (LCD), a critical image quality metric impacting diagnostic quality, before measuring CTDI(VOL). The kVp pair, flux ratio, and optimal monochromatic energy have been carefully optimized for FKS protocols prior to the comparison. Our baseline single-energy protocols were per IEC-61223-3-5 under head and body conditions except for mA, which was iteratively adjusted to match the LCD of FKS. CTDI(VOL) was measured using either a 16 cm (for head scanning) or a 32 cm (for body scanning) PMMA phantom of at least 14 cm in length. The LCD was measured using the uniform section of Catphan 600. To make the study repeatable, the automated statistical LCD measurement tool available on GE Discovery CT750 scanner was used in this work. A visual LCD phantom and a Gammex tissue characterization phantom were also employed to verify the statistical LCD measurements and to introduce various patient sizes and contrast levels.
The mean CTDI(VOL) for the head and body single-energy acquisitions was 57.5 and 29.2 mGy, respectively. The LCD was measured at 0.45% and 0.42%, respectively. The average CTDI(VOL) for FKS head and body scans was 70.4 and 33.4 mGy, respectively. The corresponding LCD was measured at 0.45% and 0.43%, respectively. The results from the visual LCD phantom and Gammex phantom supported the statistical LCD measurements.
For equal image quality as measured by low contrast detectability, the CTDI(VOL) of a FKS head and body exam is roughly 22% and 14% higher than that of a routine single-energy head and body exam, respectively, for the phantom measured.
最近,一种快速千伏切换(FKS)双能方法已经在临床和体模研究中得到了验证,展示了其有效性。由于 FKS 双能扫描涉及到在 140kVp 下更高的能量采集和更慢的机架旋转时间(例如 0.9-1 秒),而不是常规单能扫描中使用的 0.5 秒,因此人们对 FKS 双能扫描的患者剂量产生了担忧。本研究的目的是定量比较 FKS 和常规 CT 检查在体部和头部条件下的 CTDI(VOL)。
为了进行公平的比较,我们必须克服 FKS 和常规 CT 检查之间协议不匹配的困难。在本文中,我们提出在测量 CTDI(VOL)之前匹配低对比度检测能力(LCD),这是一个影响诊断质量的关键图像质量指标。在进行比较之前,我们已经仔细优化了 FKS 协议的千伏对、通量比和最佳单能。我们的基线单能协议是根据 IEC-61223-3-5 制定的,除了根据 FKS 协议匹配的毫安(mA)进行迭代调整外,其余均适用于头部和体部条件。使用至少 14cm 长的 16cm(用于头部扫描)或 32cm(用于体部扫描)PMMA 体模进行 CTDI(VOL)测量。使用 Catphan 600 的均匀部分测量 LCD。为了使研究具有可重复性,本工作中使用了通用电气 Discovery CT750 扫描仪上的自动统计 LCD 测量工具。还使用了可视化 LCD 体模和 Gammex 组织特征化体模来验证统计 LCD 测量结果,并引入各种患者大小和对比度水平。
头部和体部单能采集的平均 CTDI(VOL)分别为 57.5 和 29.2mGy。LCD 分别测量为 0.45%和 0.42%。FKS 头部和体部扫描的平均 CTDI(VOL)分别为 70.4 和 33.4mGy。相应的 LCD 分别测量为 0.45%和 0.43%。可视化 LCD 体模和 Gammex 体模的结果支持了统计 LCD 测量结果。
对于通过低对比度检测能力测量的相同图像质量,FKS 头部和体部检查的 CTDI(VOL)分别比常规单能头部和体部检查高 22%和 14%,对于所测量的体模。