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慢性脊髓损伤患者的前列腺癌患病率。

Prevalence of prostate cancer in patients with chronic spinal cord injury.

机构信息

Department of Physical Medicine and Rehabilitation, Medical College of Wisconsin, Milwaukee, WI, USA.

出版信息

PM R. 2011 Jul;3(7):633-6. doi: 10.1016/j.pmrj.2011.04.024.

Abstract

OBJECTIVE

To determine the prevalence of prostate cancer in patients with chronic spinal cord injury (SCI), with regard to the duration, level, and severity of injury.

DESIGN

Retrospective chart review study.

SETTING

Inpatient and outpatient Veterans Affairs spinal cord unit.

PARTICIPANTS

The electronic medical records of 350 veterans with chronic SCI and 344 veterans without SCI as a control group were reviewed.

MAIN OUTCOME MEASURE

Prevalence of prostate cancer in patients with chronic SCI with regard to the duration, level, and severity of injury.

RESULTS

Of 350 veterans with chronic SCI, 7 individuals (2%) had prostate cancer. In comparison, of 344 age-matched veterans without SCI, 18 (5.2%) had prostate cancer. In SCI group with prostate cancer, 2 patients had motor complete injury (American Spinal Cord Injury Association Impairment Scale [AIS] A and B), and 5 patients had motor incomplete injury (AIS C, D, and E). Patients with SCI and with prostate cancer were slightly older (mean [SD] age, 72.14 ± 8.25 years) than the control group (mean [SD] age, 69.83 ± 8.79 years) with cancer.

CONCLUSION

Findings from this study indicate a lower prevalence of prostate cancer among veterans with chronic SCI in comparison with age-matched veterans without SCI. Given the small number of patients with SCI and with prostate cancer in this study, we did not find any statistically significant correlation between the prevalence of prostate cancer and the level, duration, and severity of injury.

摘要

目的

确定慢性脊髓损伤(SCI)患者中前列腺癌的患病率,考虑损伤的持续时间、水平和严重程度。

设计

回顾性图表研究。

地点

退伍军人事务部脊髓病房的住院和门诊。

参与者

回顾了 350 名慢性 SCI 退伍军人和 344 名无 SCI 作为对照组的电子病历。

主要观察指标

慢性 SCI 患者中前列腺癌的患病率,考虑损伤的持续时间、水平和严重程度。

结果

在 350 名慢性 SCI 退伍军人中,有 7 人(2%)患有前列腺癌。相比之下,在 344 名年龄匹配的无 SCI 退伍军人中,有 18 人(5.2%)患有前列腺癌。在患有前列腺癌的 SCI 组中,有 2 名患者为完全运动损伤(美国脊髓损伤协会损伤量表 [AIS] A 和 B),5 名患者为不完全运动损伤(AIS C、D 和 E)。患有 SCI 和前列腺癌的患者年龄稍大(平均[SD]年龄,72.14 ± 8.25 岁),高于患有癌症的对照组(平均[SD]年龄,69.83 ± 8.79 岁)。

结论

本研究结果表明,与年龄匹配的无 SCI 退伍军人相比,慢性 SCI 退伍军人中前列腺癌的患病率较低。鉴于本研究中患有 SCI 和前列腺癌的患者人数较少,我们没有发现前列腺癌的患病率与损伤的水平、持续时间和严重程度之间存在任何统计学上的显著相关性。

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