• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

慢性脊髓损伤患者的前列腺癌患病率。

Prevalence of prostate cancer in patients with chronic spinal cord injury.

机构信息

Department of Physical Medicine and Rehabilitation, Medical College of Wisconsin, Milwaukee, WI, USA.

出版信息

PM R. 2011 Jul;3(7):633-6. doi: 10.1016/j.pmrj.2011.04.024.

DOI:10.1016/j.pmrj.2011.04.024
PMID:21777862
Abstract

OBJECTIVE

To determine the prevalence of prostate cancer in patients with chronic spinal cord injury (SCI), with regard to the duration, level, and severity of injury.

DESIGN

Retrospective chart review study.

SETTING

Inpatient and outpatient Veterans Affairs spinal cord unit.

PARTICIPANTS

The electronic medical records of 350 veterans with chronic SCI and 344 veterans without SCI as a control group were reviewed.

MAIN OUTCOME MEASURE

Prevalence of prostate cancer in patients with chronic SCI with regard to the duration, level, and severity of injury.

RESULTS

Of 350 veterans with chronic SCI, 7 individuals (2%) had prostate cancer. In comparison, of 344 age-matched veterans without SCI, 18 (5.2%) had prostate cancer. In SCI group with prostate cancer, 2 patients had motor complete injury (American Spinal Cord Injury Association Impairment Scale [AIS] A and B), and 5 patients had motor incomplete injury (AIS C, D, and E). Patients with SCI and with prostate cancer were slightly older (mean [SD] age, 72.14 ± 8.25 years) than the control group (mean [SD] age, 69.83 ± 8.79 years) with cancer.

CONCLUSION

Findings from this study indicate a lower prevalence of prostate cancer among veterans with chronic SCI in comparison with age-matched veterans without SCI. Given the small number of patients with SCI and with prostate cancer in this study, we did not find any statistically significant correlation between the prevalence of prostate cancer and the level, duration, and severity of injury.

摘要

目的

确定慢性脊髓损伤(SCI)患者中前列腺癌的患病率,考虑损伤的持续时间、水平和严重程度。

设计

回顾性图表研究。

地点

退伍军人事务部脊髓病房的住院和门诊。

参与者

回顾了 350 名慢性 SCI 退伍军人和 344 名无 SCI 作为对照组的电子病历。

主要观察指标

慢性 SCI 患者中前列腺癌的患病率,考虑损伤的持续时间、水平和严重程度。

结果

在 350 名慢性 SCI 退伍军人中,有 7 人(2%)患有前列腺癌。相比之下,在 344 名年龄匹配的无 SCI 退伍军人中,有 18 人(5.2%)患有前列腺癌。在患有前列腺癌的 SCI 组中,有 2 名患者为完全运动损伤(美国脊髓损伤协会损伤量表 [AIS] A 和 B),5 名患者为不完全运动损伤(AIS C、D 和 E)。患有 SCI 和前列腺癌的患者年龄稍大(平均[SD]年龄,72.14 ± 8.25 岁),高于患有癌症的对照组(平均[SD]年龄,69.83 ± 8.79 岁)。

结论

本研究结果表明,与年龄匹配的无 SCI 退伍军人相比,慢性 SCI 退伍军人中前列腺癌的患病率较低。鉴于本研究中患有 SCI 和前列腺癌的患者人数较少,我们没有发现前列腺癌的患病率与损伤的水平、持续时间和严重程度之间存在任何统计学上的显著相关性。

相似文献

1
Prevalence of prostate cancer in patients with chronic spinal cord injury.慢性脊髓损伤患者的前列腺癌患病率。
PM R. 2011 Jul;3(7):633-6. doi: 10.1016/j.pmrj.2011.04.024.
2
Prevalence of testosterone deficiency after spinal cord injury.脊髓损伤后睾酮缺乏症的患病率。
PM R. 2011 Oct;3(10):929-32. doi: 10.1016/j.pmrj.2011.07.008.
3
Prostate cancer diagnosed in spinal cord-injured patients is more commonly advanced stage than in able-bodied patients.
Urology. 2004 Mar;63(3):509-12. doi: 10.1016/j.urology.2003.10.022.
4
Incidence of fractures in a cohort of veterans with chronic multiple sclerosis or traumatic spinal cord injury.患有慢性多发性硬化症或创伤性脊髓损伤的退伍军人队列中的骨折发生率。
Arch Phys Med Rehabil. 2008 Feb;89(2):237-43. doi: 10.1016/j.apmr.2007.08.144.
5
Surgical treatment for prostate cancer in patients with prior spinal cord injury.
Ann Surg Oncol. 2005 Aug;12(8):674-8. doi: 10.1245/ASO.2005.10.010. Epub 2005 Jun 22.
6
Males aging with a spinal cord injury: prevalence of cardiovascular and metabolic conditions.男性随着脊髓损伤而衰老:心血管和代谢状况的流行率。
Arch Phys Med Rehabil. 2012 Jan;93(1):90-5. doi: 10.1016/j.apmr.2011.07.201.
7
Spinal cord injury and cholelithiasis.脊髓损伤与胆结石
Hepatobiliary Pancreat Dis Int. 2004 Nov;3(4):595-8.
8
Prostate activity and prostate cancer in spinal cord injury.脊髓损伤中的前列腺活动与前列腺癌
Prostate Cancer Prostatic Dis. 2006;9(2):115-20. doi: 10.1038/sj.pcan.4500865. Epub 2006 Mar 14.
9
Gram-negative intravascular catheter-related bacteremia in patients with spinal cord injury.脊髓损伤患者革兰氏阴性菌血管内导管相关菌血症
Arch Phys Med Rehabil. 2008 Feb;89(2):339-42. doi: 10.1016/j.apmr.2007.08.151.
10
Sleep apnea syndrome in chronic spinal cord injury: associated factors and treatment.慢性脊髓损伤中的睡眠呼吸暂停综合征:相关因素与治疗
Arch Phys Med Rehabil. 2000 Oct;81(10):1334-9. doi: 10.1053/apmr.2000.9398.

引用本文的文献

1
The Crosstalk between Nerves and Cancer-A Poorly Understood Phenomenon and New Possibilities.神经与癌症之间的相互作用——一种了解甚少的现象及新的可能性
Cancers (Basel). 2024 May 15;16(10):1875. doi: 10.3390/cancers16101875.
2
Race and Age-Related PSA Testing Disparities in Spinal Cord Injured Men: Analysis of National Veterans Health Administration Data.脊髓损伤男性中与种族和年龄相关的前列腺特异性抗原检测差异:基于美国退伍军人健康管理局全国数据的分析
Fed Pract. 2023 Aug;40(Suppl 3):S50-S57. doi: 10.12788/fp.0392. Epub 2023 Aug 23.
3
The nerve growth factor-delivered signals in prostate cancer and its associated microenvironment: when the dialogue replaces the monologue.
神经生长因子在前列腺癌及其相关微环境中传递的信号:当对话取代独白时。
Cell Biosci. 2023 Mar 20;13(1):60. doi: 10.1186/s13578-023-01008-4.
4
Neurobiology of cancer: Definition, historical overview, and clinical implications.癌症的神经生物学:定义、历史概述及临床意义。
Cancer Med. 2022 Feb;11(4):903-921. doi: 10.1002/cam4.4488. Epub 2021 Dec 24.
5
Muscarinic receptors promote castration-resistant growth of prostate cancer through a FAK-YAP signaling axis.毒蕈碱型乙酰胆碱受体通过 FAK-YAP 信号通路促进去势抵抗性前列腺癌的生长。
Oncogene. 2020 May;39(20):4014-4027. doi: 10.1038/s41388-020-1272-x. Epub 2020 Mar 23.
6
Tumour innervation and neurosignalling in prostate cancer.前列腺癌的肿瘤神经支配和神经信号转导。
Nat Rev Urol. 2020 Feb;17(2):119-130. doi: 10.1038/s41585-019-0274-3. Epub 2020 Jan 14.
7
Risk of prostate cancer in men with spinal cord injury: A systematic review and meta-analysis.脊髓损伤男性的前列腺癌风险:系统评价和荟萃分析。
Asian J Androl. 2018 Nov-Dec;20(6):555-560. doi: 10.4103/aja.aja_31_18.
8
Risk of Nongenitourinary Cancers in Patients With Spinal Cord Injury: A Population-based Cohort Study.脊髓损伤患者发生非泌尿生殖系统癌症的风险:一项基于人群的队列研究。
Medicine (Baltimore). 2016 Jan;95(2):e2462. doi: 10.1097/MD.0000000000002462.
9
Prostate cancer and neuroendocrine differentiation: more neuronal, less endocrine?前列腺癌与神经内分泌分化:神经元更多,内分泌细胞更少?
Front Oncol. 2015 Mar 3;5:37. doi: 10.3389/fonc.2015.00037. eCollection 2015.
10
The osteoblastic and osteoclastic interactions in spinal metastases secondary to prostate cancer.前列腺癌继发脊柱转移中破骨细胞与成骨细胞的相互作用。
Cancer Growth Metastasis. 2013 Nov 27;6:61-80. doi: 10.4137/CGM.S12769. eCollection 2013.