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经导管主动脉瓣植入术治疗失败的外科生物瓣主动脉瓣:从概念到临床应用和评估(第 1 部分)。

Transcatheter aortic valve implantation for failing surgical aortic bioprosthetic valve: from concept to clinical application and evaluation (part 1).

机构信息

Department of Cardiovascular Surgery, German Heart Center, Munich, Germany.

出版信息

JACC Cardiovasc Interv. 2011 Jul;4(7):721-32. doi: 10.1016/j.jcin.2011.03.016.

Abstract

With an aging population, improvement in life expectancy, and significant increase in the use of bioprosthetic valves, structural valve deterioration will become more and more prevalent. The operative mortality for an elective redo aortic valve surgery is reported to range from 2% to 7%, but this percentage can increase to more than 30% in high-risk and nonelective patients. Because transcatheter aortic valve (TAV)-in-surgical aortic valve (SAV) implantation represents a minimally invasive alternative to conventional redo surgery, it may prove to be safer and just as effective as redo surgery. Of course, prospective comparisons with a large number of patients and long-term follow-up are required to confirm these potential advantages. It is axiomatic that knowledge of the basic construction and dimensions, radiographic identification, and potential failure modes of SAV bioprostheses is fundamental in understanding key principles involved in TAV-in-SAV implantation. The goals of this paper are: 1) to review the classification, physical characteristics, and potential failure modes of surgical bioprosthetic aortic valves; and 2) to discuss patient selection and procedural techniques relevant to TAV-in-SAV implantation.

摘要

随着人口老龄化、预期寿命的提高以及生物假体瓣膜使用的显著增加,结构性瓣膜退化将变得越来越普遍。择期再次主动脉瓣手术的手术死亡率据报道在 2%至 7%之间,但在高危和非选择性患者中,这一百分比可能会增加到 30%以上。由于经导管主动脉瓣(TAV)-在手术主动脉瓣(SAV)植入术代表了一种比传统再次手术更微创的替代方法,它可能被证明与再次手术一样安全有效。当然,需要进行前瞻性的、大量患者的比较和长期随访,以确认这些潜在的优势。不言而喻,了解 SAV 生物假体的基本结构和尺寸、影像学识别以及潜在的失效模式,对于理解 TAV 在 SAV 植入中的关键原则至关重要。本文的目的是:1)回顾手术生物假体主动脉瓣的分类、物理特性和潜在失效模式;2)讨论与 TAV 在 SAV 植入相关的患者选择和程序技术。

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