Aiyama H, Nakai K, Yamamoto T, Nariai T, Kumada H, Ishikawa E, Isobe T, Endo K, Takada T, Yoshida F, Shibata Y, Matsumura A
Department of Neurosurgery, Graduate School of Comprehensive Human Science, University of Tsukuba, Tennodai, Tsukuba, Japan.
Appl Radiat Isot. 2011 Dec;69(12):1819-22. doi: 10.1016/j.apradiso.2011.04.031. Epub 2011 Jul 20.
We have evaluated the efficacy and safety of boron neutron capture therapy (BNCT) for recurrent glioma and malignant brain tumor using a new protocol. One of the two patients enrolled in this trial is a man with recurrent glioblastoma and the other is a woman with anaplastic meningioma. Both are still alive and no severe adverse events have been observed. Our findings suggest that NCT will be safe as a palliative therapy for malignant brain tumors.
我们使用一种新方案评估了硼中子俘获疗法（BNCT）治疗复发性胶质瘤和恶性脑肿瘤的疗效及安全性。该试验纳入的两名患者中，一名是复发性胶质母细胞瘤男性患者，另一名是间变性脑膜瘤女性患者。两人均存活，且未观察到严重不良事件。我们的研究结果表明，BNCT作为恶性脑肿瘤的姑息治疗将是安全的。
