Dreiseidler Timo, Alarabi Nuri, Ritter Lutz, Rothamel Daniel, Scheer Martin, Zöller Joachim E, Mischkowski Robert A
Faculty Member, Department of Craniomaxillofacial and Plastic Surgery, University of Cologne, Cologne, Germany.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011 Sep;112(3):367-74. doi: 10.1016/j.tripleo.2011.04.001. Epub 2011 Jul 20.
The aim of this study was to compare the performance of cone-beam computerized tomography (CBCT) with multislice CT (MSCT) and single photon emission CT (SPECT) in the detection of bone invasion from oral malignancies.
In this prospective investigation, 77 patients with histologically proven malignancy of the oral cavity received MSCT, CBCT, and SPECT imaging of the head presurgically. Radiologic evaluations were compared with histopathologic examinations of the resected tumor specimens. Receiver operating characteristic (ROC) analysis as well as the sensitivity, specificity, and positive and negative predictive values were calculated.
The sensitivity, specificity, positive predictive value, and negative predictive value for MSCT were 0.8, 1.0, 1.0, and 0.75, respectively; for CBCT 0.92, 0.965, 0.98, and 0.875; and for SPECT 0.91, 0.4, 0.7, and 0.75. ROC analysis showed area under the curve values of 0.894 (95% confidence interval [CI] 0.806-0.982) for MSCT; 0.931 (95% CI 0.835-1.000) for CBCT, and 0.716 (95% CI 0.566-0.866) for SPECT.
CBCT is accurate in predicting malignancies' bone involvement and can compete with MSCT and SPECT in detecting bone invasion in patients with oral malignancies.
本研究旨在比较锥形束计算机断层扫描（CBCT）与多层螺旋CT（MSCT）及单光子发射计算机断层扫描（SPECT）在检测口腔恶性肿瘤骨侵犯方面的性能。
在这项前瞻性研究中，77例经组织学证实为口腔恶性肿瘤的患者在术前接受了头部的MSCT、CBCT和SPECT成像。将放射学评估结果与切除肿瘤标本的组织病理学检查结果进行比较。计算受试者操作特征（ROC）分析以及敏感度、特异度、阳性预测值和阴性预测值。
MSCT的敏感度、特异度、阳性预测值和阴性预测值分别为0.8、1.0、1.0和0.75；CBCT分别为0.92、0.965、0.98和0.875；SPECT分别为0.91、0.4、0.7和0.75。ROC分析显示，MSCT的曲线下面积值为0.894（95%置信区间[CI]0.806 - 0.982）；CBCT为0.931（95%CI 0.
