Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine, 820 Harrison Ave, FGH Building, 3rd Floor, Boston, MA 02118, USA.
Radiology. 2011 Aug;260(2):332-54. doi: 10.1148/radiol.11101359.
Osteoarthritis (OA) is the most frequent form of arthritis, with major implications for individual and public health care without effective treatment available. The field of joint imaging, and particularly magnetic resonance (MR) imaging, has evolved rapidly owing to technical advances and the application of these to the field of clinical research. Cartilage imaging certainly is at the forefront of these developments. In this review, the different aspects of OA imaging and cartilage assessment, with an emphasis on recent advances, will be presented. The current role of radiography, including advances in the technology for joint space width assessment, will be discussed. The development of various MR imaging techniques capable of facilitating assessment of cartilage morphology and the methods for evaluating the biochemical composition of cartilage will be presented. Advances in quantitative morphologic cartilage assessment and semiquantitative whole-organ assessment will be reviewed. Although MR imaging is the most important modality in imaging of OA and cartilage, others such as ultrasonography play a complementary role that will be discussed briefly.
骨关节炎（OA）是最常见的关节炎形式，对个人和公共医疗保健有重大影响，但目前尚无有效的治疗方法。由于技术进步以及将这些技术应用于临床研究领域，关节成像领域，特别是磁共振（MR）成像领域发展迅速。软骨成像无疑处于这些发展的前沿。在这篇综述中，将介绍 OA 成像和软骨评估的不同方面，并重点介绍最新进展。将讨论放射摄影的当前作用，包括关节间隙宽度评估技术的进步。将介绍各种能够促进软骨形态评估的 MR 成像技术以及评估软骨生化成分的方法。将回顾定量形态软骨评估和全器官半定量评估的进展。尽管 MR 成像在 OA 和软骨成像中是最重要的方式，但其他成像方式如超声也具有互补作用，我们将简要讨论。
