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[特发性溃疡性直肠结肠炎患者的巨细胞病毒和单纯疱疹病毒抗体]

[Cytomegalovirus and herpes simplex virus antibodies in patients with idiopathic ulcerative rectocolitis].

作者信息

Riegler G, Piscitelli A, Di Simone A, Esposito C, Sodano G, Tarro G

机构信息

Cattedra di Patologia Medica, I Facoltà di Medicina e Chirurgia, Università degli Studi di Napoli.

出版信息

Minerva Med. 1990 Dec;81(12):861-4.

PMID:2177863
Abstract

The total and fractioned titres of circulating anticytomegalovirus (CMV) and antiherpesvirus (HSV) antibodies were evaluated in 63 idiopathic ulcerative proctocolitis patients in follow-up. The population was disaggregated applying criteria related to the stage of the disease: duration, extension, number of observed relapses over the follow-up. It was noted that just the anti-HSV antibodies were correlated in a statistically significant way to the extension (p less than 0.025) and duration (p less than 0.025) of the disease. We believe that this behaviour is a manifestation of the disease and that the antiHSV titration may be included in a score of evaluation during the follow-up.

摘要

在63例接受随访的特发性溃疡性直肠结肠炎患者中,评估了循环抗巨细胞病毒(CMV)和抗疱疹病毒(HSV)抗体的总滴度和分级滴度。根据疾病阶段相关标准对人群进行分类:病程、病变范围、随访期间观察到的复发次数。结果发现,仅抗HSV抗体与疾病的病变范围(p<0.025)和病程(p<0.025)存在统计学显著相关性。我们认为这种现象是该疾病的一种表现,并且抗HSV滴度测定可纳入随访期间的评估评分中。

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