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[古巴人类免疫缺陷病毒(HIV)感染患者单纯疱疹病毒和巨细胞病毒的随访血清学研究]

[Follow-up serological study of herpes simplex and cytomegalovirus in Cuban patients infected with human immunodeficiency virus (HIV)].

作者信息

Resik S, Santana E, Rivero J, Pérez A B, Kourí V, Larralde O

机构信息

Instituto de Medicina Tropical Pedro Kourí.

出版信息

Rev Cubana Med Trop. 1997;49(2):113-9.

PMID:9685973
Abstract

The evolution serological response against the herpes simplex virus and citomegalovirus in HIV infected patients grouped into different stages of the disease was studied. Fluctuations in the TPG of antibodies were observed in these values in a cyclical way through time. There was a greater significant difference among the TPG of antibodies against HSV in the group of asymptomatic patients compared with AIDS patients and with those who died. There is a marked decrease in the TPG of antibodies against HSV and CMV approximately one year before the death of patients.

摘要

研究了处于疾病不同阶段的HIV感染患者针对单纯疱疹病毒和巨细胞病毒的血清学反应演变。随着时间推移,这些数值中抗体的总蛋白含量(TPG)呈周期性波动。与艾滋病患者及死亡患者相比,无症状患者组中针对HSV抗体的TPG存在更大的显著差异。在患者死亡前约一年,针对HSV和CMV抗体的TPG显著下降。

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