Zhang J H, Sato M, Noguchi K, Tohyama M
Department of Anatomy II, Osaka University Medical School, Japan.
Neurosci Lett. 1990 Nov 13;119(2):257-60. doi: 10.1016/0304-3940(90)90847-3.
The expression of mRNAs encoding different beta subunits (beta 1, beta 2 and beta 3) of GABAA receptor in the rat olfactory bulb and some of its related areas was investigated by in situ hybridization histochemistry. The beta 3 subunit mRNA was expressed in most of the cells in these regions such as periglomerular cells, tufted cells, mitral cells and granule cells in olfactory bulb, and the cells in anterior olfactory nucleus, piriform cortex and olfactory tubercle. However, only several kinds of these cells contained beta 2 subunit mRNA such as tufted cells and mitral cells of olfactory bulb, and the cells in anterior olfactory nucleus and piriform cortex. The beta 1 subunit mRNA was only detected in the mitral cells of olfactory bulb.
采用原位杂交组织化学方法，研究了大鼠嗅球及其部分相关区域中编码GABAA受体不同β亚基（β1、β2和β3）的mRNA的表达情况。β3亚基mRNA在这些区域的大多数细胞中表达，如嗅球中的小球周细胞、丛状细胞、僧帽细胞和颗粒细胞，以及前嗅核、梨状皮质和嗅结节中的细胞。然而，只有几种这类细胞含有β2亚基mRNA，如嗅球的丛状细胞和僧帽细胞，以及前嗅核和梨状皮质中的细胞。β1亚基mRNA仅在嗅球的僧帽细胞中检测到。
