Department of General Pediatrics, University Children's Hospital Münster, Germany.
Horm Res Paediatr. 2011;76(3):202-7. doi: 10.1159/000329049. Epub 2011 Jul 22.
The purpose of the present study was to analyze resting energy expenditure (REE), hormonal parameters and lipid profile in small for gestational age (SGA) moderately preterm infants compared to their appropriate for gestational age (AGA) counterparts in the first week after birth.
REE was measured in all participants using indirect calorimetry. Blood samples of all infants were collected at the same study point together with indirect calorimetry measurements.
A total of 32 infants including 16 preterm infants born SGA and 16 AGA preterm neonates were recruited for the study, with a mean gestational age of 35 ± 1 weeks in both groups. REE values in the SGA group were significantly increased compared to the AGA group data after birth (p < 0.002). Low-density lipoprotein levels from the AGA group were significantly higher (p = 0.002) when compared to the SGA infants. No other clinical differences in hormonal parameters, lipid profile or blood pressure levels were identified between the two groups.
In addition to low birth weight, intrauterine growth retardation is associated with a statistically significant increase in REE in SGA moderately premature infants shortly after birth, which requires further investigation when establishing nutritional recommendations in this cohort.
本研究旨在分析小于胎龄儿（SGA）早产儿与适于胎龄儿（AGA）早产儿在出生后第一周的静息能量消耗（REE）、激素参数和血脂谱。
所有参与者均采用间接测热法测量 REE。所有婴儿的血样均在同一研究点与间接测热法测量同时采集。
本研究共纳入 32 名婴儿，包括 16 名出生时 SGA 的早产儿和 16 名 AGA 早产儿，两组的平均胎龄均为 35 ± 1 周。出生后，SGA 组的 REE 值明显高于 AGA 组（p < 0.002）。与 SGA 婴儿相比，AGA 组的低密度脂蛋白水平明显升高（p = 0.002）。两组之间在激素参数、血脂谱或血压水平方面没有其他临床差异。
除了出生体重低之外，宫内生长迟缓与 SGA 中度早产儿出生后 REE 的统计学显著增加有关，在为该队列制定营养建议时需要进一步研究。
