Sartori Ana Lucia, Minamisava Ruth, Avelino Mariza Martins, Martins Cleusa Alves
Universidade Federal de Mato Grosso, Sinop, MT, Brasil.
Rev Bras Ginecol Obstet. 2011 Feb;33(2):93-8. doi: 10.1590/s0100-72032011000200007.
to estimate the prevalence and risk factors associated with seropositivity for Toxoplasma gondii in pregnant women.
a cross-sectional retrospective study based on the records of women screened for toxoplasmosis by the Pregnancy Protection Program in 2008, living in Goiânia (GO). These records were connected to records from the database of the National Information System on Live Births from the State of Goiás. The process occurred in three phases, with 10,316 records being paired for analysis, among the 12,846 initial records. The following variables were evaluated in this process: woman's name, age, date of birth, estimated date of delivery, date of infant birth and household information. Anti-Toxoplasma gondii antibodies were detected with the Q-Preven Toxo IgG and IgMin tests in dried blood samples collected on filter paper. The χ2 test and χ2 test for trend were used for data analysis, and the odds ratio (OR) was used to estimate the chance of association between exposure and outcome.
the prevalence of infection was 67.7%, with 0.7% of the samples presenting anti-Toxoplasma gondii IgM and IgG reagents. Out of these, only three did not undergo confirmatory testing in venous blood. The median interval between the screening and the new collection of venous blood was of 12.5 days, and from screening to confirmatory test and avidity it was of 20 days. The variables associated with exposure were: age 20-30 years, OR=1.6 and ≥31 years, OR=1.8; brown skin color, OR=1.4, and black skin color, OR=1.6; and education of 8-11 years, OR=0.7, and ≥12 years of education, OR=0.6.
a high prevalence of infection was estimated among the studied pregnant women. The associated factors that were found found should be considered during prenatal care, along with educational activities for the prevention of infection and assessment of serological status of seronegative pregnant women.
评估孕妇弓形虫血清阳性的患病率及相关危险因素。
一项基于2008年在戈亚尼亚（GO）通过妊娠保护计划筛查弓形虫病的女性记录的横断面回顾性研究。这些记录与戈亚斯州国家活产信息系统数据库中的记录相关联。该过程分三个阶段进行，在12,846条初始记录中，有10,316条记录配对进行分析。在此过程中评估了以下变量：女性姓名、年龄、出生日期、预计分娩日期、婴儿出生日期和家庭信息。在滤纸上采集的干血样本中，使用Q-Preven Toxo IgG和IgM检测来检测抗弓形虫抗体。采用χ2检验和趋势χ2检验进行数据分析，并使用比值比（OR）来估计暴露与结果之间关联的可能性。
感染患病率为67.7%，0.7%的样本呈现抗弓形虫IgM和IgG试剂阳性。其中，只有三例未进行静脉血确诊检测。筛查与新采集静脉血之间间隔的中位数为12.5天，从筛查到确诊检测和亲和力检测为20天。与暴露相关的变量为：年龄20 - 30岁，OR = 1.6，≥31岁，OR = 1.8；棕色皮肤，OR = 1.4，黑色皮肤，OR = 1.6；受教育8 - 11年，OR = 0.7，≥12年教育，OR = 0.6。
在所研究的孕妇中估计感染患病率较高。在产前护理期间，应考虑所发现的相关因素，同时开展预防感染的教育活动并评估血清阴性孕妇的血清学状态。
