Silva Thiago George Cabral, Polido Júlia Gomes Fernandes, Pinheiro Maurício Vieira, Silva André Luís de Freitas, Goldbach Laerte, Mascaro Vera Lúcia Degaspare Monte, Serracarbassa Pedro Durães, Araújo Maria Emília Xavier dos Santos
Hospital do Servidor Público Estadual de São Paulo, SP, Brasil.
Arq Bras Oftalmol. 2011 Mar-Apr;74(2):102-5. doi: 10.1590/s0004-27492011000200006.
To compare the intraocular pressure (IOP) pre and post LASIK, correlating it to changes in central corneal thickness (CCT) and average simulated keratometry (K), as well as verifying the results of a corrective formula previously proposed.
Longitudinal prospective study conducted in outpatients that underwent to LASIK. Patients underwent complete ophthalmic examination, previously and 2 months after the surgery. Intraocular pressure was evaluated with Goldmann applanation tonometer between 9 am and 11 am, average simulated keratometry was evaluated using corneal topography and central corneal thickness was measured with ultrasound pachymetry, been considered the average of three measurements. Two patients were excluded due to surgery or eye disease, and previous use of topical steroids over the past three months. The surgeries were performed according to standard procedures. The formula [real IOP = IOP measured + (540 - ECC)/71 + (43 - K)/2.7 + 0.75 mmHg] proposed for correcting intraocular pressure was used.
Fifteen eyes of eight patients were evaluated, age ranged from 24 to 46 years (mean: 31.37 ± 7.27). There was a statistically significant difference between the measurements of intraocular pressure, central corneal thickness and average simulated keratometry pre and post-LASIK. (p=0.0001). It was observed that each 1D corrected underestimated the IOP 1.06 ± 0.59 mmHg (0.11 a 1.89 mmHg). The use of the corrective formula lead to 80% of eyes within 2.50 mmHg of preoperative intraocular pressure. Although, the two sets of data are statistically different (p=0.0266).
Post LASIK eyes presented lower intraocular pressure than preoperatively. Intraocular pressure was moderately correlated to central corneal thickness and weakly correlated to average simulated keratometry. With the use of the corrective formula, we were able to determine that 80% were within 2.50 mmHg of the preoperative intraocular pressure.
比较准分子激光原位角膜磨镶术（LASIK）前后的眼压（IOP），并将其与中央角膜厚度（CCT）和平均模拟角膜曲率（K）的变化相关联，同时验证先前提出的校正公式的结果。
对接受LASIK手术的门诊患者进行纵向前瞻性研究。患者在手术前和手术后2个月接受了全面的眼科检查。上午9点至11点之间使用Goldmann压平眼压计评估眼压，使用角膜地形图评估平均模拟角膜曲率，并用超声角膜测厚仪测量中央角膜厚度，取三次测量的平均值。两名患者因手术或眼部疾病以及过去三个月内曾使用局部类固醇而被排除。手术按照标准程序进行。使用提出的校正眼压的公式[实际IOP = 测量的IOP +（540 - ECC）/71 +（43 - K）/2.7 + 0.75 mmHg]。
评估了8例患者的15只眼，年龄范围为24至46岁（平均：31.37±7.27）。LASIK前后眼压、中央角膜厚度和平均模拟角膜曲率的测量值之间存在统计学上的显著差异（p = 0.0001）。观察到每矫正1D眼压低估1.06±0.59 mmHg（0.11至1.89 mmHg）。使用校正公式使8０％的眼眼压在术前眼压的2.50 mmHg范围内。尽管两组数据在统计学上存在差异（p = 0.0266）。
LASIK术后眼的眼压低于术前。眼压与中央角膜厚度呈中度相关，与平均模拟角膜曲率呈弱相关。通过使用校正公式，我们能够确定80％的眼眼压在术前眼压的2.50 mmHg范围内。
