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分析扁桃体切除术后出血的预后因素。

Analysis of prognostic factors for postoperative bleeding after tonsillectomy.

机构信息

Department of Anaesthesiology, School of Medicine, Kyung Hee University, Seoul, Korea.

出版信息

Eur Arch Otorhinolaryngol. 2012 Mar;269(3):977-81. doi: 10.1007/s00405-011-1697-5. Epub 2011 Jul 16.

DOI:10.1007/s00405-011-1697-5
PMID:21779841
Abstract

Postoperative bleeding is the most frequent surgical complication after tonsillectomy and may be associated with increased mortality rate. We have, therefore, analyzed factors associated with and prognostic for bleeding after tonsillectomy. The 2,254 patients who underwent tonsillectomy under general anesthesia at our institution from January 2005 to December 2009 were divided into bleeding and non-bleeding groups, and their demographic and clinical characteristics were compared. Age, administration of steroid immediately after general anesthesia, absence of administration of non-steroidal anti-inflammatory drugs, and the surgeon's experience were significantly associated with bleeding. In contrast, gender, chief complaints, performance of associated surgery, and type of anesthetic were not associated with postoperative bleeding. Hemorrhage after tonsillectomy was associated with the administration of steroids and with the non-administration of non-steroidal anti-inflammatory drugs.

摘要

术后出血是扁桃体切除术后最常见的手术并发症,可能与死亡率增加有关。因此,我们分析了与扁桃体切除术后出血相关的因素及其预后。2005 年 1 月至 2009 年 12 月,在我院接受全身麻醉下扁桃体切除术的 2254 例患者被分为出血组和非出血组,比较了他们的人口统计学和临床特征。年龄、全身麻醉后立即给予类固醇、未给予非甾体抗炎药以及外科医生的经验与出血显著相关。相比之下,性别、主要诉求、相关手术的执行情况以及麻醉类型与术后出血无关。扁桃体切除术后出血与类固醇的使用以及非甾体抗炎药的未使用有关。

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Analysis of prognostic factors for postoperative bleeding after tonsillectomy.分析扁桃体切除术后出血的预后因素。
Eur Arch Otorhinolaryngol. 2012 Mar;269(3):977-81. doi: 10.1007/s00405-011-1697-5. Epub 2011 Jul 16.
2
Post-tonsillectomy haemorrhage more common than previously described--an institutional chart review.扁桃体切除术后出血比先前描述的更常见——一项机构图表回顾
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Intraoperative intravenous ibuprofen use is not associated with increased post-tonsillectomy bleeding.术中静脉使用布洛芬与扁桃体切除术后出血增加无关。
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[Risk of hemorrhage after adenoidectomy and tonsillectomy. Value of the preoperative determination of partial thromboplastin time, prothrombin time and platelet count].[腺样体切除术和扁桃体切除术后出血的风险。术前测定部分凝血活酶时间、凝血酶原时间和血小板计数的价值]
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15-year audit of post-tonsillectomy haemorrhage at Dunedin Hospital.达尼丁医院扁桃体切除术后出血的15年审计
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Systematic Review and Meta-Analysis of the Association Between Non-Steroidal Anti-Inflammatory Drugs and Operative Bleeding in the Perioperative Period.非甾体抗炎药与围手术期手术出血相关性的系统评价和荟萃分析。
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本文引用的文献

1
Dexamethasone administration and postoperative bleeding risk in children undergoing tonsillectomy.扁桃体切除术后儿童使用地塞米松与术后出血风险
Arch Otolaryngol Head Neck Surg. 2010 Aug;136(8):766-72. doi: 10.1001/archoto.2010.133.
2
Determination of optimum dosage of intraoperative single dose dexamethasone in pediatric tonsillectomy and adenotonsillectomy.小儿扁桃体切除术和腺样体扁桃体切除术中术中单次剂量地塞米松最佳剂量的确定。
Int J Pediatr Otorhinolaryngol. 2009 Nov;73(11):1513-5. doi: 10.1016/j.ijporl.2009.06.001. Epub 2009 Jul 10.
3
A national survey of the anesthetic management of tonsillectomy surgery in children.
Risk factors of post-tonsillectomy hemorrhage in adults.
成人扁桃体切除术后出血的危险因素
Laryngoscope Investig Otolaryngol. 2020 Nov 14;5(6):1056-1062. doi: 10.1002/lio2.488. eCollection 2020 Dec.
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Effect of Body Mass Index on Posttonsillectomy Hemorrhage.体重指数对扁桃体切除术后出血的影响。
Biomed Res Int. 2017;2017:9610267. doi: 10.1155/2017/9610267. Epub 2017 May 7.
5
Surgical technique and post-tonsillectomy hemorrhage: a single institution's retrospective study.手术技术与扁桃体切除术后出血:一项单机构回顾性研究
Eur Arch Otorhinolaryngol. 2017 Feb;274(2):947-952. doi: 10.1007/s00405-016-4271-3. Epub 2016 Aug 20.
6
Factors influencing morbidity after paediatric tonsillectomy: a study of 18,712 patients in the National Tonsil Surgery Register in Sweden.影响小儿扁桃体切除术后发病率的因素:瑞典国家扁桃体手术登记处18712例患者的研究
Eur Arch Otorhinolaryngol. 2016 Aug;273(8):2249-56. doi: 10.1007/s00405-016-4001-x. Epub 2016 Mar 28.
7
Comparison of postoperative bleeding between submucosal uvulopalatopharyngoplasty and tonsillectomy.悬雍垂腭咽成形术与扁桃体切除术术后出血情况的比较。
J Res Med Sci. 2014 Apr;19(4):310-3.
8
Preoperative coagulation screening prior to tonsillectomy in adults: current practice and recommendations.成人扁桃体切除术前凝血筛查:当前实践与建议。
Eur Arch Otorhinolaryngol. 2013 Mar;270(3):1099-104. doi: 10.1007/s00405-012-2099-z. Epub 2012 Jul 12.
一项关于儿童扁桃体切除术麻醉管理的全国性调查。
Paediatr Anaesth. 2009 Feb;19(2):145-52. doi: 10.1111/j.1460-9592.2008.02860.x. Epub 2008 Dec 18.
4
Dexamethasone and risk of nausea and vomiting and postoperative bleeding after tonsillectomy in children: a randomized trial.地塞米松与儿童扁桃体切除术后恶心呕吐及出血风险:一项随机试验
JAMA. 2008 Dec 10;300(22):2621-30. doi: 10.1001/jama.2008.794.
5
Subhypnotic propofol infusion plus dexamethasone is more effective than dexamethasone alone for the prevention of vomiting in children after tonsillectomy.亚催眠剂量丙泊酚输注联合地塞米松在预防儿童扁桃体切除术后呕吐方面比单独使用地塞米松更有效。
Paediatr Anaesth. 2008 Sep;18(9):878-83. doi: 10.1111/j.1460-9592.2008.02675.x.
6
Society for Ambulatory Anesthesia guidelines for the management of postoperative nausea and vomiting.门诊麻醉学会术后恶心呕吐管理指南。
Anesth Analg. 2007 Dec;105(6):1615-28, table of contents. doi: 10.1213/01.ane.0000295230.55439.f4.
7
15-year audit of post-tonsillectomy haemorrhage at Dunedin Hospital.达尼丁医院扁桃体切除术后出血的15年审计
ANZ J Surg. 2007 Jul;77(7):579-82. doi: 10.1111/j.1445-2197.2007.04154.x.
8
There is no dose-escalation response to dexamethasone (0.0625-1.0 mg/kg) in pediatric tonsillectomy or adenotonsillectomy patients for preventing vomiting, reducing pain, shortening time to first liquid intake, or the incidence of voice change.在小儿扁桃体切除术或腺样体扁桃体切除术中,对于预防呕吐、减轻疼痛、缩短首次摄入液体的时间或声音改变的发生率,地塞米松(0.0625 - 1.0毫克/千克)不存在剂量递增反应。
Anesth Analg. 2007 May;104(5):1052-8, tables of contents. doi: 10.1213/01.ane.0000263276.52287.3b.
9
Non-steroidal anti-inflammatory drugs and perioperative bleeding in paediatric tonsillectomy.非甾体类抗炎药与小儿扁桃体切除术中的围手术期出血
Cochrane Database Syst Rev. 2005 Apr 18(2):CD003591. doi: 10.1002/14651858.CD003591.pub2.
10
Perioperative adenotonsillectomy management in children: current practices.儿童围手术期腺样体扁桃体切除术的管理:当前实践
Laryngoscope. 2003 Apr;113(4):592-7. doi: 10.1097/00005537-200304000-00002.