Yoon Tae-Ho, Jung Sang-Hee, Kim Dong-Pyo
Center of Applied Microfluidic Chemistry, Chungnam National University, Daejeon 305-764, Korea.
J Nanosci Nanotechnol. 2011 May;11(5):4295-9. doi: 10.1166/jnn.2011.3649.
We report the successful fabrication of preceramic polymer allylhydridopolycarbosilane (AHPCS) derived microchannels with excellent organic solvent resistance and optical transparency via economic imprinting process, followed by UV and post thermal curing process at 160 degrees C for 3 h. The microchemical performance of the fabricated microreactors was evaluated by choosing two model micro chemical reactions under organic solvent conditions; syntheses of 2-aminothiazole in DMF and dimethylpyrazole in THF, and compared with glass-based microreactor having identical dimensions and batch system with analogy. It is clear that AHPCS derived microreactor showed excellent solvent resistance and chemical stability compare with glass derived microreactor made by high cost of photolithography and thermal bonding process. The novel preceramic polymer derived microreactors showed reliable mechanical and chemical stability and conversion yields compare with that of glass derived microreactors, which is very promising for developing an integrated microfluidics by adopting available microstructuring techniques of the polymers.
我们报道了通过经济的压印工艺成功制备出具有优异耐有机溶剂性和光学透明性的陶瓷前驱体聚合物烯丙基氢化聚碳硅烷（AHPCS）衍生微通道，随后在160℃下进行紫外线和后热固化处理3小时。通过在有机溶剂条件下选择两个模型微化学反应来评估所制备微反应器的微化学性能；在N，N - 二甲基甲酰胺（DMF）中合成2 - 氨基噻唑以及在四氢呋喃（THF）中合成二甲基吡唑，并与具有相同尺寸的玻璃基微反应器和类似的间歇系统进行比较。显然，与通过高成本的光刻和热键合工艺制造的玻璃衍生微反应器相比，AHPCS衍生的微反应器表现出优异的耐溶剂性和化学稳定性。与玻璃衍生的微反应器相比，新型陶瓷前驱体聚合物衍生的微反应器显示出可靠的机械和化学稳定性以及转化率，这对于通过采用聚合物可用的微结构化技术开发集成微流控技术非常有前景。
