Krupatkin A I
Fiziol Cheloveka. 2011 May-Jun;37(3):50-6.
The methodology of quantitative estimation of information value in microvascular networks is proposed for the first time with the use of wavelet analysis of skin blood flow oscillations registrated by laser Doppler flowmetry at 30 healthy persons and 56 patients after hand injuries and diseases. It includes calculation of relative indices for the information preservation, the predomination of preserved information and the efficacy of information. The most deviation from multistable information regimen happened after formation of resonance oscillations: the general quantity of information decreased but the preservation of predominated information increased. The preservation of trophic myogenic information predominated after reduction of sympathetic influences. With the increase in the number of information channels the quantity of information increased but its preservation varied. Sensory peptidergic nerve fibres were activated during local heating to 34 degrees C at dorsal forearm skin. This information was the most effective at the beginning of heating during the growth of blood flow to the plateau level. Blood flow oscillations represented in wavelet spectrum serve as operators build on the basis of effective information. These oscillations play not only hemodynamic role but are the bearers of information in microvascular networks.
首次提出了一种利用激光多普勒血流仪记录的30名健康人和56名手部受伤及患病患者皮肤血流振荡的小波分析，对微血管网络中的信息价值进行定量估计的方法。它包括计算信息保存的相对指标、保存信息的主导地位和信息的功效。共振振荡形成后，与多稳态信息状态的偏差最大：信息总量减少，但主导信息的保存增加。交感神经影响减弱后，营养性肌源性信息的保存占主导地位。随着信息通道数量的增加，信息量增加但其保存情况有所不同。在前臂背侧皮肤局部加热至34摄氏度时，感觉肽能神经纤维被激活。在加热开始时，血流增加至平台期水平的过程中，该信息最为有效。小波频谱中呈现的血流振荡作为基于有效信息构建的算子。这些振荡不仅起血液动力学作用，而且是微血管网络中信息的载体。
