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Computational approaches for the design of modulators targeting protein-protein interactions.
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Environment- and sequence-dependence of helical type in membrane-spanning peptides composed of β3-amino acids.
Org Lett. 2011 Jul 1;13(13):3474-7. doi: 10.1021/ol201218y. Epub 2011 Jun 9.
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De novo design and molecular assembly of a transmembrane diporphyrin-binding protein complex.
J Am Chem Soc. 2010 Nov 10;132(44):15516-8. doi: 10.1021/ja107487b.
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Computational design of a self-assembling β-peptide oligomer.
Org Lett. 2010 Nov 19;12(22):5142-5. doi: 10.1021/ol102092r. Epub 2010 Oct 14.
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Specificity for homooligomer versus heterooligomer formation in integrin transmembrane helices.
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Inhibition of gamma-secretase activity by helical beta-peptide foldamers.
J Am Chem Soc. 2009 Jun 3;131(21):7353-9. doi: 10.1021/ja9001458.
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Computationally designed peptide inhibitors of protein-protein interactions in membranes.
Biochemistry. 2008 Aug 19;47(33):8600-6. doi: 10.1021/bi800687h. Epub 2008 Jul 22.
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Foldamers with heterogeneous backbones.
Acc Chem Res. 2008 Oct;41(10):1399-408. doi: 10.1021/ar800009n. Epub 2008 Jul 1.

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