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食管切除术后的空肠造口术:证据回顾与当前实践。

Jejunostomy after oesophagectomy: a review of evidence and current practice.

机构信息

Royal Infirmary of Edinburgh, 51 Little France Crescent, Old Dalkeith Road, Edinburgh EH16 4SA, UK.

出版信息

Proc Nutr Soc. 2011 Aug;70(3):316-20. doi: 10.1017/S0029665111000553.

Abstract

Patients undergoing oesophagectomy often have nutritional needs at the time of diagnosis and in the post-operative period. The aim of this article is to review the current literature and report on the author's experience of routine feeding jejunostomy insertion following oesophagectomy. The records of forty-eight consecutive patients undergoing oesphagectomy under the author's care were reviewed. Although the evidence of benefit of peri-operative feeding in patients undergoing oesophagectomy is limited, there is a clear need to establish a feeding route at the time of surgery. Oesophagectomy is associated with a mortality rate of 5-10% and a morbidity rate of 30-40% even in high-volume specialist centres. Over 50% of patients developing complications will require an alternative to oral feeding beyond 30 d. The enteral route is preferred in terms of safety and cost. A surgical feeding jejunostomy is associated with a low complication rate and a mortality rate of less than 1%. In forty-eight patients undergoing oesophagectomy the average weight loss at 6 months was 8·4 kg with only 8% regaining their pre-operative weight. Large reductions in weight at 6 months post-operatively were recorded irrespective of the development of post-operative complications or early recurrent disease. Routine jejunostomy insertion is recommended to ensure adequate nutrition in patients who develop post-operative complications and for those patients with long-term reduced appetite and poor oral intake.

摘要

接受食管切除术的患者在诊断时和术后期间通常有营养需求。本文旨在回顾当前文献,并报告作者在食管切除术后常规进行喂养空肠造口术的经验。回顾了作者治疗的 48 例连续食管切除术患者的记录。尽管在接受食管切除术的患者中进行围手术期喂养的益处证据有限,但在手术时建立喂养途径是明确需要的。即使在高容量专科中心,食管切除术的死亡率也为 5-10%,发病率为 30-40%。超过 50%的发生并发症的患者将需要替代 30 天以上的口服喂养。从安全性和成本角度来看,肠内途径是首选。手术喂养空肠造口术与低并发症发生率和低于 1%的死亡率相关。在 48 例行食管切除术的患者中,6 个月时的平均体重减轻为 8.4 公斤,只有 8%的患者恢复术前体重。术后 6 个月体重大幅减轻,无论是否发生术后并发症或早期复发性疾病。建议常规进行空肠造口术,以确保发生术后并发症的患者和长期食欲减退和口腔摄入不足的患者获得足够的营养。

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