多发性对称性脂肪瘤病。
Multiple symmetric lipomatosis.
机构信息
Federal University of Minas Gerais, Belo Horizonte/MG, Brazil.
出版信息
J Cutan Med Surg. 2011 Jul-Aug;15(4):230-5. doi: 10.2310/7750.2011.10026.
BACKGROUND
Multiple symmetric lipomatosis (MSL) is a relatively uncommon entity of unknown etiology characterized by symmetrically subcutaneous accumulation of nonencapsulated adipose tissue. Approximately 200 to 300 cases have been published.
OBJECTIVES
The aims of this article are to report the case of a 58-year-old Brazilian patient with MSL and provide a comprehensive overview of the current concepts concerning this disease.
METHODS
Our search yielded 28 articles on MSL, including case reports and reviews of the literature.
RESULTS
MSL predominantly affects Mediterranean males with a history of chronic alcohol abuse. It is usually asymptomatic and may be associated with diabetes mellitus, hyperlipidemia, hyperuricemia, macrocytic anemia, and oral cancer. Surgical resection is the best treatment option.
CONCLUSION
The case reported is a classic presentation of MSL; however, it is particularly uncommon owing to the association with immune thrombocytopenic purpura. This association has been described only once in the medical literature.
背景
多发性对称性脂肪瘤病（MSL）是一种病因不明的相对罕见疾病，其特征为非包膜性脂肪组织在身体两侧对称堆积。目前已有大约 200 到 300 例相关报道。
目的
本文报道了一例 58 岁巴西患者的 MSL 病例，并对该疾病的现有概念进行了全面综述。
方法
我们对 MSL 的相关文献进行了检索，共获得 28 篇文章，包括病例报告和文献综述。
结果
MSL 主要影响有慢性酗酒史的地中海男性，通常无症状，可能与糖尿病、高脂血症、高尿酸血症、巨幼细胞性贫血和口腔癌相关。手术切除是最佳治疗选择。
结论
本例报告为 MSL 的典型表现，但由于与免疫性血小板减少性紫癜相关，因此较为罕见。这种关联仅在医学文献中描述过一次。
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