多发性硬化症中括约肌控制运动通路的电生理学
Electrophysiology of motor pathways for sphincter control in multiple sclerosis.
作者信息
Mathers S E, Ingram D A, Swash M
机构信息
Sir Alan Parks Physiology Unit, St Mark's Hospital, London.
出版信息
J Neurol Neurosurg Psychiatry. 1990 Nov;53(11):955-60. doi: 10.1136/jnnp.53.11.955.
Abstract
The central and peripheral motor pathways serving striated sphincter muscle function were studied using cortical and lumbar transcutaneous electrical stimulation, pudendal nerve stimulation and sphincter electromyography in 23 patients with multiple sclerosis (MS), and sphincter disturbance, including incontinence of urine or faeces, urinary voiding dysfunction, or constipation. The central motor conduction time was significantly increased in the MS group compared to controls (p less than 0.05). Damage to both the upper and lower motor neuron pathways can contribute to sphincter disturbance in MS. The latter may be due to coexisting pathology or to involvement of the conus medullaris by MS.
摘要
采用皮层和腰部经皮电刺激、阴部神经刺激及括约肌肌电图，对23例患有多发性硬化症（MS）且存在括约肌功能障碍（包括尿失禁或大便失禁、排尿功能障碍或便秘）的患者，研究了支配横纹肌括约肌功能的中枢和外周运动通路。与对照组相比，MS组的中枢运动传导时间显著延长（p<0.05）。上、下运动神经元通路的损伤均可导致MS患者的括约肌功能障碍。后者可能是由于并存的病变或MS累及脊髓圆锥所致。
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