Faculty of Engineering, University of Malaya, 50603 Kuala Lumpur, Malaysia.
J Mech Behav Biomed Mater. 2011 Oct;4(7):1384-95. doi: 10.1016/j.jmbbm.2011.05.009. Epub 2011 May 17.
Despite dental implantation being a great success, one of the key issues facing it is a mismatch of mechanical properties between engineered and native biomaterials, which makes osseointegration and bone remodeling problematical. Functionally graded material (FGM) has been proposed as a potential upgrade to some conventional implant materials such as titanium for selection in prosthetic dentistry. The idea of an FGM dental implant is that the property would vary in a certain pattern to match the biomechanical characteristics required at different regions in the hosting bone. However, matching the properties does not necessarily guarantee the best osseointegration and bone remodeling. Little existing research has been reported on developing an optimal design of an FGM dental implant for promoting long-term success. Based upon remodeling results, metaheuristic algorithms such as the genetic algorithms (GAs) and simulated annealing (SA) have been adopted to develop a multi-objective optimal design for FGM implantation design. The results are compared with those in literature.
尽管牙科植入物取得了巨大的成功,但它面临的一个关键问题是工程生物材料和天然生物材料之间机械性能不匹配,这使得骨整合和骨重塑成为问题。功能梯度材料(FGM)已被提议作为一些传统植入物材料(如钛)的潜在升级材料,以用于修复牙科。FGM 牙科植入物的理念是,该特性将以某种模式变化,以匹配宿主骨中不同区域所需的生物力学特性。然而,匹配特性并不一定能保证最佳的骨整合和骨重塑。目前关于开发 FGM 牙科植入物以促进长期成功的最佳设计的研究很少。基于重塑结果,已经采用了元启发式算法(如遗传算法(GA)和模拟退火(SA))来开发 FGM 植入物设计的多目标优化设计。将结果与文献中的结果进行比较。