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与空中喷雾接触有机磷农药导致的 QT 间期延长和 ST-T 改变。

Long QT and ST-T change associated with organophosphate exposure by aerial spray.

机构信息

Department of Anesthesiology, Tokyo Women's Medical University, East Medical Center, Daini Hospital, Nishiogu, Arakawa, Tokyo 116-8567, Japan.

出版信息

Environ Toxicol Pharmacol. 2006 Jul;22(1):40-5. doi: 10.1016/j.etap.2005.11.008. Epub 2006 Jan 18.

Abstract

The relation between the electrocardiographic manifestation and the subjective symptoms accompanying organophosphate pesticide exposure caused by aerial spray was investigated. The study included 39 patients with a diagnosis of organophosphate poisoning, who visited A-clinic within 24h of exposure to aerial spray of organophosphate pesticide in Gumma Prefecture, from July 2001 to September 2001. Ages ranged from 3 to 82 years. Thirty-five patients were female. Three were diagnosed as severe, 11 moderate, and 25 mild, judged from the score of subjective symptoms. Electrocardiographic abnormalities were bradycardia (<50) 2; prolonged PQ interval 4; prolonged QTc interval (>430ms) 22; nonspecific ST-T change 35; supraventricular arrhythmia 13; and ventricular premature complex with R on T 1. Prolonged QTc interval developed in 2-3 severe cases, 4-11 moderate cases, and 16-25 mild cases. QT prolongation, ST-T change and arrhythmia were detected for some patients exposed to organophosphate by aerial spray.

摘要

调查了因空中喷洒农药而导致的有机磷农药接触者的心电图表现与伴随的主观症状之间的关系。该研究包括 39 名 2001 年 7 月至 9 月期间在群马县因接触空中喷洒的有机磷农药而在 A 诊所就诊的有机磷中毒患者,年龄在 3 至 82 岁之间。35 名女性患者。根据主观症状评分,有 3 名患者被诊断为重度,11 名中度,25 名轻度。心电图异常包括心动过缓(<50)2 例;PQ 间期延长 4 例;QTc 间期延长(>430ms)22 例;非特异性 ST-T 改变 35 例;室上性心律失常 13 例;R on T 上的室性期前收缩 1 例。2-3 例重度、4-11 例中度和 16-25 例轻度病例出现 QTc 间期延长。一些接触有机磷农药的患者出现 QT 延长、ST-T 改变和心律失常。

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