Department of Nursing, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Arch Psychiatr Nurs. 2011 Aug;25(4):269-83. doi: 10.1016/j.apnu.2010.09.002. Epub 2010 Dec 3.
The purpose of this cross-sectional research study was to examine factors affecting medication adherence in Thai individuals with schizophrenia. The Common-Sense Model of Illness Representation was used to guide the study. Two hundred twenty-five subjects met the inclusion criteria and were interviewed. Variables of interest focused on experience of medication side effects, therapeutic alliance, social support, illness representation, and behavior change with medication adherence. Results indicated that therapeutic alliance and the experience of medication side effects enhanced illness representation, which in turn led to an intention to change adherence behavior. Social support did not alter illness representation or adherence behavior. Because illness representation positively influenced patients' intention to change adherence behavior, mental health nurses should promote patients' perception about their illness to enhance medication adherence.
本横断面研究旨在探讨影响泰国精神分裂症患者药物治疗依从性的因素。采用疾病认知综合模式指导研究。符合纳入标准的 225 名受试者接受了访谈。研究的关注点集中在药物副作用体验、治疗联盟、社会支持、疾病认知和药物治疗依从性改变行为等方面。结果表明，治疗联盟和药物副作用体验增强了疾病认知，进而导致改变服药依从性的意愿。社会支持并未改变疾病认知或服药依从性。由于疾病认知对患者改变服药依从性的意愿有积极影响，精神科护士应增强患者对疾病的认知，以提高药物治疗的依从性。
