Department of Elderly Psychiatry, Parnassia Bavo Group Psychiatric Institute, Netherlands.
Behav Res Ther. 2011 Oct;49(10):588-96. doi: 10.1016/j.brat.2011.05.010. Epub 2011 Jul 23.
Although rumination is an important mediator of depressive symptoms, there is insufficient proof that an intervention that specifically targets rumination ameliorates the clinical condition of, depressed patients. This study investigates whether a time-limited cognitive behavioral intervention (Competitive Memory Training, or COMET for depressive rumination) is an effective treatment for depression and rumination. This intervention was tested in older adult depressed outpatients. A total of 93 patients (aged ≥ 65 years with major depression and suffering from rumination) were treated in small groups according to the COMET protocol in addition to their regular treatment. Patients were randomized to two treatment conditions: 7 weeks of COMET + treatment-as-usual (TAU) versus TAU only. COMET + TAU showed a significant improvement in depression and rumination compared with TAU alone. This study shows that the transdiagnostic COMET protocol for depressive rumination might also be successful in treating depression and rumination in older adults.
虽然反刍是抑郁症状的一个重要中介,但没有足够的证据表明专门针对反刍的干预措施可以改善抑郁患者的临床状况。本研究调查了限时认知行为干预(竞争性记忆训练,或 COMET 治疗抑郁反刍)是否是治疗抑郁和反刍的有效方法。该干预措施在老年抑郁门诊患者中进行了测试。共有 93 名患者(年龄≥65 岁,患有重度抑郁症并伴有反刍)按照 COMET 方案在常规治疗之外进行小组治疗。患者被随机分为两种治疗条件:7 周的 COMET+常规治疗(TAU)与仅 TAU。COMET+TAU 与仅 TAU 相比,在抑郁和反刍方面有显著改善。本研究表明,针对抑郁反刍的跨诊断 COMET 方案也可能成功治疗老年人的抑郁和反刍。