Epilepsy Center, Ramos Mejía Hospital, Buenos Aires, Argentina.
Epilepsy Res. 2011 Nov;97(1-2):37-44. doi: 10.1016/j.eplepsyres.2011.06.016. Epub 2011 Jul 23.
It is well established that naming deficits can be found in temporal lobe epilepsy (TLE). The aim of this study was to determine in Spanish speakers with pharmacoresistant TLE the characteristics of subjective naming difficulties and to examine performance in a definition task and a picture task in left TLE and right TLE. We observed that almost one-third of patients report frequent and severe word finding problems during spontaneous speech. In naming tests, our patients exhibited delayed times for finding words. Even if the target word was identified and semantically activated, there was difficulty with lexical access, which improved when a phonetic cue was given. Left TLE patients derived a lower benefit from phonetic cues in accessing words, even when the word is known and recognized semantically. These findings were not related to any demographic or clinical characteristics analyzed. The fact that the only weakly lateralized variable has been a lexical access facilitation measurement could support a lexical access hypothesis for naming deficits in TLE.
已证实颞叶癫痫(TLE)患者存在命名缺陷。本研究旨在确定西班牙裔药物难治性 TLE 患者主观命名困难的特征,并检查左 TLE 和右 TLE 患者在定义任务和图片任务中的表现。我们观察到,近三分之一的患者在自发讲话中经常报告严重的找词问题。在命名测试中,我们的患者在找词时花费了更多的时间。即使目标词被识别并在语义上激活,也难以进行词汇检索,而在提供语音提示时则有所改善。即使单词是已知的且在语义上被识别,左 TLE 患者在使用语音提示获取单词时也无法获得更多的好处。这些发现与分析的任何人口统计学或临床特征无关。唯一弱侧化的变量是词汇检索促进测量,这一事实可能支持 TLE 命名缺陷的词汇检索假说。