The Monsall Unit, Department of Infectious Diseases and Tropical Medicine, North Manchester General Hospital, Manchester, UK.
QJM. 2011 Nov;104(11):921-31. doi: 10.1093/qjmed/hcr111. Epub 2011 Jul 22.
Encephalitic syndromes are a common medical emergency. The importance of early diagnosis and appropriate treatment is paramount. If initial investigations for infectious agents prove negative, other diagnoses must be considered promptly. Autoimmune encephalitides are being increasingly recognized as important (and potentially reversible) non-infectious causes of an encephalitic syndrome. We describe four patients with autoimmune encephalitis--3 auto-antibody positive, 1 auto-antibody negative--treated during the last 18 months. A comprehensive review of the literature in this expanding area will be of interest to the infectious diseases, general medical and neurology community.
脑炎综合征是一种常见的医学急症。早期诊断和适当治疗至关重要。如果针对感染因子的初始检查结果为阴性，则必须迅速考虑其他诊断。自身免疫性脑炎作为一种重要（且可能是可逆转的）非传染性脑炎综合征病因，正日益受到关注。我们描述了在过去 18 个月中治疗的 4 例自身免疫性脑炎患者，其中 3 例抗体阳性，1 例抗体阴性。对这一不断扩展领域的文献进行全面回顾，将引起传染病、普通内科和神经科医生的兴趣。
