亮氨酸拉链基序在大肠杆菌细胞分裂蛋白 FtsL 和 FtsB 结合中的作用。
Role of leucine zipper motifs in association of the Escherichia coli cell division proteins FtsL and FtsB.
机构信息
Institut Pasteur, CNRS URA 2185, Unité de Biochimie des Interactions Macromoléculaires, Département de Biologie Structurale et Chimie, 28 rue du Dr Roux, 75724 Paris Cedex 15, France.
出版信息
J Bacteriol. 2011 Sep;193(18):4988-92. doi: 10.1128/JB.00324-11. Epub 2011 Jul 22.
Abstract
FtsL and FtsB are two inner-membrane proteins that are essential constituents of the cell division apparatus of Escherichia coli. In this study, we demonstrate that the leucine zipper-like (LZ) motifs, located in the periplasmic domain of FtsL and FtsB, are required for an optimal interaction between these two essential proteins.
摘要
FtsL 和 FtsB 是两种内膜蛋白，是大肠杆菌细胞分裂装置的基本组成部分。在这项研究中，我们证明了位于 FtsL 和 FtsB 周质域的亮氨酸拉链样 (LZ) 基序对于这两种必需蛋白之间的最佳相互作用是必需的。
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