Belgadi B, Richaud P, Lagarde P, Dilhuydy J M, Faucher A, Traissac L, Stoll D, Pigneux J
Fondation Bergonié, Bordeaux.
Ann Otolaryngol Chir Cervicofac. 1990;107(1):53-8.
Cancer of the cavum is a rare condition in France. These tumors have, however, a poor prognosis and in general occur in young subjects. While radiotherapy would appear to be the best mean of ensuring local control, life expectancy depends solely on distant metastases. Analysis of a series of 58 cases treated at the Fondation Bergonié from 1975 to 1985 demonstrated a 30% five year survival rate. Among the 25 cases of recurrence, 1 was exclusively local and 6 were loco-regional (T and N), while 18 patients presented metastatic progression, either exclusively, or with local or lymph node failure. The prognostic factors found in this series were: age, extension beyond the cavum, the dose of radiotherapy. Results in the literature in terms of survival remain poor, especially in advanced stages and the future perspectives for better control of this disease remain early diagnosis and other forms of therapy such as combined chemotherapy and radiotherapy.
口腔癌在法国是一种罕见病症。然而,这些肿瘤预后较差,且一般发生在年轻患者身上。虽然放射治疗似乎是确保局部控制的最佳手段,但预期寿命仅取决于远处转移情况。对1975年至1985年在贝贡尼基金会接受治疗的58例病例进行分析,结果显示五年生存率为30%。在25例复发病例中,1例为单纯局部复发,6例为局部区域复发(T和N),而18例患者出现了转移进展,或为单纯转移进展,或伴有局部或淋巴结病变。该系列病例中发现的预后因素包括:年龄、超出口腔的病变范围、放射治疗剂量。文献中的生存结果仍然较差,尤其是在晚期,更好地控制这种疾病的未来前景仍在于早期诊断以及其他治疗方式,如联合化疗和放疗。