Pimentel E
Centro Nacional de Genetica, Universidad Central de Venezuela, Caracas.
Ann Clin Lab Sci. 1990 Jan-Feb;20(1):36-55.
The colony-stimulating factors (CSFs) are hematopoietic growth factors (HGFs) involved in regulating the formation of nonlymphoid blood cells. A brief review of the different types of CSFs and their biological properties is presented. The current nomenclature of CSFs and other HGFs is confused by the use of terms and abbreviations based on particular effects on target cells. However, a given cell is frequently recognized by more than one HGF/CSF, and a given HGF/CSF may recognize different types of target cells, including in some cases nonhematopoietic cells. A number-based nomenclature is universally used for the interleukins. Since the macrophage CSF (M-CSF) and the granulocyte-macrophage CSF (GM-CSF) have been designated previously as CSF-1 and CSF-2, respectively, the author proposes the designation of the granulocyte CSF (G-CSF) as CSF-3.
集落刺激因子（CSF）是参与调节非淋巴细胞形成的造血生长因子（HGF）。本文简要综述了不同类型的CSF及其生物学特性。由于基于对靶细胞的特定作用使用术语和缩写，CSF和其他HGF的当前命名法存在混淆。然而，一种给定的细胞常常可被不止一种HGF/CSF识别，并且一种给定的HGF/CSF可能识别不同类型的靶细胞，在某些情况下包括非造血细胞。白细胞介素普遍使用基于数字的命名法。由于巨噬细胞CSF（M-CSF）和粒细胞-巨噬细胞CSF（GM-CSF）先前已分别被指定为CSF-1和CSF-2，作者建议将粒细胞CSF（G-CSF）指定为CSF-3。
