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星状神经节阻滞疗法治疗心室电风暴:一例报告

Stellate ganglion block therapy in management of ventricular electrical storm: A case report.

作者信息

Huang Chaoqun, Shu Shangzhi, Zhou Miaomiao, Sun Zhenming, Li Shuyan

机构信息

Department of Cardiovascular Medicine, The First Bethune Hospital of Jilin University, Changchun, China.

出版信息

Heliyon. 2024 Sep 10;10(19):e37724. doi: 10.1016/j.heliyon.2024.e37724. eCollection 2024 Oct 15.

Abstract

Sympathetic overactivity is a recognized underlying mechanism contributing to the pathogenesis of ventricular electrical storm (VES). The growing body of evidence supports the efficacy of stellate ganglion block (SGB) in attenuating myocardial sympathetic tone, rendering it a valuable adjunctive therapy for managing VES. This case report presents the clinical details of a 60-year-old patient admitted for ventricular tachycardia (VT), necessitating the implantation of an implantable cardioverter defibrillator (ICD) to mitigate the risk of fatal ventricular arrhythmias (VAs). Subsequently, the patient received repeated antitachycardia pacing (ATP) therapy due to persistent symptomatic VT episodes. SGB was contemplated due to the patient's hemodynamic instability during episodes of VT and the ineffectiveness of pharmacotherapy. Initially, complete suppression of VT was achieved for 3 days using local anesthesia, followed by partial suppression via pulsed radiofrequency (PRF), culminating in sustained relief for 3 months following continuous radiofrequency (CRF) therapy. Different methods of SGB elicited varied responses in this patient. CRF appeared to be more effective than PRF and conventional local anesthetics. CRF ablation of the stellate ganglion for refractory VAs offers a potential therapeutic option.

摘要

交感神经过度活跃是公认的导致心室电风暴(VES)发病机制的潜在机制。越来越多的证据支持星状神经节阻滞(SGB)在减弱心肌交感神经张力方面的有效性,使其成为治疗VES的一种有价值的辅助疗法。本病例报告介绍了一名60岁因室性心动过速(VT)入院患者的临床细节,该患者需要植入植入式心脏复律除颤器(ICD)以降低致命性室性心律失常(VA)的风险。随后,由于持续性有症状的VT发作,患者接受了反复的抗心动过速起搏(ATP)治疗。由于患者在VT发作期间存在血流动力学不稳定且药物治疗无效,因此考虑进行SGB。最初,使用局部麻醉实现了VT的完全抑制达3天,随后通过脉冲射频(PRF)实现了部分抑制,最终在连续射频(CRF)治疗后持续缓解达3个月。不同的SGB方法在该患者中引起了不同的反应。CRF似乎比PRF和传统局部麻醉剂更有效。对于难治性VA,星状神经节的CRF消融提供了一种潜在的治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/668b/11462198/c55e128d80dc/gr1.jpg

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