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硬脊膜囊横截面积与单节段腰椎管狭窄症经皮松解粘连术的疗效无关。

Dural sac cross-sectional area does not correlate with efficacy of percutaneous adhesiolysis in single level lumbar spinal stenosis.

机构信息

Daegu Wooridul Spine Hospital Daegu, South Korea.

出版信息

Pain Physician. 2011 Jul-Aug;14(4):377-82.

Abstract

BACKGROUND

Spinal stenosis is a narrowing of the spinal canal, which causes mechanical compression of spinal nerve roots. The compression of these nerve roots can cause low back pain and/or leg pain, as well as neurogenic claudication. Lumbar epidural steroid injections have commonly been used in patients with lumbar spinal stenosis (LSS). In cases that are refractory to epidural steroid injections, percutaneous epidural adhesiolysis has been used.

OBJECTIVE

The aim of our study is to determine the relationship between the severity of spinal stenosis and the participants' response to adhesiolysis, and to evaluate the mid-term effectiveness of adhesiolysis.

STUDY DESIGN

A prospective observational study.

METHODS

Sixty-six patients with degenerative LSS were enrolled in this prospective study. All participants underwent lumbar spine magnetic resonance imaging (MRI). The cross-sectional area of the dural sac was measured on the transverse angled sections through the central part of the disc on conventional MR images. All percutaneous adhesiolyses were performed in the operating room. One hour following the procedure, 6 mL of 8% sodium chloride solution was infused during 30 minutes in the recovery room while the patient underwent monitoring. Outcome measures were obtained using the 5-point patient satisfaction scale at 2 weeks and 6 months post-treatment. To evaluate outcome predictors, we divided the participants into 2 groups according to their response to treatment.

LIMITATIONS

Secondary outcomes were not measured and the study did not include a long-term follow-up period.

RESULTS

Improvement (including reports of slightly improved, much improved, and no pain) was observed in 49 participants (74.2%) at 2 weeks and 45 participants (66.7%) at 6 months after the procedure. The dural sac cross-sectional area (DSCSA) did not differ between participants who reported improvement and those who did not. There was no statistically significant correlation between pain relief and DSCSA, age, or participant sex.

CONCLUSION

Percutaneous adhesiolysis was shown to be effective for the treatment of LSS, with mid-term result, without affecting DSCSA.

摘要

背景

脊柱狭窄症是椎管狭窄,它会导致脊神经根机械性受压。这些神经根受压会引起腰痛和/或腿痛,以及神经性跛行。腰椎硬膜外类固醇注射常用于腰椎管狭窄症(LSS)患者。在硬膜外类固醇注射无效的情况下,已经使用了经皮硬膜外粘连松解术。

目的

我们的研究旨在确定脊柱狭窄症的严重程度与患者对粘连松解术的反应之间的关系,并评估粘连松解术的中期效果。

研究设计

前瞻性观察性研究。

方法

本前瞻性研究纳入了 66 例退行性 LSS 患者。所有参与者均接受腰椎磁共振成像(MRI)检查。在常规 MRI 图像中穿过椎间盘中央部分的横断角切片上测量硬脑膜囊的横截面积。所有经皮粘连松解术均在手术室进行。在手术后 1 小时,在恢复室进行 30 分钟的 8%氯化钠溶液输注,同时对患者进行监测。在治疗后 2 周和 6 个月时,使用 5 分制患者满意度量表获得结果。为了评估结果预测因素,我们根据患者对治疗的反应将参与者分为 2 组。

局限性

未测量次要结果,且该研究未包括长期随访期。

结果

在手术后 2 周和 6 个月时,49 名(74.2%)和 45 名(66.7%)参与者报告有改善(包括略有改善、明显改善和无疼痛)。在报告有改善和无改善的参与者之间,硬脑膜囊横截面积(DSCSA)没有差异。疼痛缓解与 DSCSA、年龄或参与者性别之间无统计学显著相关性。

结论

经皮粘连松解术对治疗 LSS 有效,具有中期效果,而不影响 DSCSA。

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