Department of Anesthesiology and Pain Medicine, Daegu Wooridul Spine Hospital, Daegu, South Korea.
Pain Physician. 2013 Jul-Aug;16(4):353-8.
Cervical central stenosis (CCS) is a narrowing of the spinal canal that can cause mechanical compression of the spinal nerve and roots, leading to neck pain and/or radicular pain. Cervical epidural steroid injections are commonly used in the treatment of CCS. After failure of epidural steroid injections, the next sequential step is percutaneous adhesiolysis with a targeted drug delivery.
The aim of our study is to evaluate the effectiveness of percutaneous cervical epidural adhesiolysis in patients with chronic posterior neck pain and upper extremity pain due to CCS.
This was a preliminary, prospective study.
Thirty-nine patients with CCS were enrolled and all subjects underwent cervical spine magnetic resonance imaging. All patients received percutaneous adhesiolysis and appropriate placement of a Racz catheter, followed by an injection of 5 mL of 0.2 % preservative-free ropivacaine containing 1,500 units of hyaluronidase and 4 mg of dexamethasone. In the recovery room, each patient also received 6 mL of 10% hypertonic sodium chloride solution, after which the catheter was removed. Outcome measures were obtained using a 5-point patient's satisfaction scale at 2 weeks and at 6 months post-treatment. To evaluate treatment effectiveness, we divided the patients into 2 groups according to their treatment response.
Secondary outcomes were not measured. The study did not include a long-term follow-up period or control group.
Improvement designated as reports of moderate pain, little pain, and no pain was observed in 30 patients (77.0 %) at 2 weeks and 28 patients (71.8 %) at 6 months after the procedure. There was no statistically significant correlation between pain relief and the severity of CCS.
Percutaneous adhesiolysis utilizing local anesthetic steroids and hypertonic sodium chloride solution may be an effective management strategy in patients with chronic posterior neck and upper extremity pain due to cervical central spinal stenosis, although there is no correlation between therapeutic response and the grade of CCS.
颈椎中央管狭窄症(CCS)是椎管狭窄的一种,可导致脊髓神经根受压,引起颈部疼痛和/或神经根痛。颈椎硬膜外类固醇注射是治疗 CCS 的常用方法。硬膜外类固醇注射失败后,下一步是经皮粘连松解术,同时进行靶向药物输送。
本研究旨在评估经皮颈椎硬膜外粘连松解术治疗因 CCS 引起的慢性颈后疼痛和上肢疼痛的有效性。
这是一项初步的前瞻性研究。
共纳入 39 例 CCS 患者,所有患者均行颈椎磁共振成像检查。所有患者均接受经皮粘连松解术和适当放置 Racz 导管,然后注射 5 毫升 0.2%无防腐剂罗哌卡因,内含 1500 单位透明质酸酶和 4 毫克地塞米松。在恢复室,每位患者还接受 6 毫升 10%高渗氯化钠溶液,之后取出导管。采用 5 分制患者满意度量表在治疗后 2 周和 6 个月时获得疗效指标。为了评估治疗效果,我们根据患者的治疗反应将患者分为两组。
未测量次要结局。该研究未包括长期随访期或对照组。
2 周后,30 例(77.0%)患者和 6 个月后 28 例(71.8%)患者报告中度疼痛、轻度疼痛和无疼痛,改善明显。疼痛缓解与 CCS 严重程度之间无显著相关性。
在因颈椎中央椎管狭窄症引起的慢性颈后和上肢疼痛患者中,局部麻醉类固醇和高渗氯化钠溶液的经皮粘连松解术可能是一种有效的治疗策略,尽管治疗反应与 CCS 分级之间无相关性。