Bhaijee Feriyl, Bell Diana
University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USA.
Case Rep Med. 2011;2011:357301. doi: 10.1155/2011/357301. Epub 2011 Jul 17.
An 86-year-old woman presented with osteonecrosis of the mandible following bisphosphonate therapy for multiple myeloma, and underwent surgical debridement and multiple dental extractions. Histopathologic examination of the necrotic bone fragments revealed acute osteomyelitis with mixed flora and organisms morphologically consistent with Entamoeba gingivalis. In addition to oral scrapings and sputum, E. gingivalis has been identified in specimens obtained from the uterus, cervix, neck lymph nodes, and lung. It is rarely found in lesions of the head and neck. We present an unusual case of E. gingivalis in acute osteomyelitis of the mandible, following bisphosphonate therapy for multiple myeloma. To our knowledge, this is the first reported case of E. gingivalis in association with osteomyelitis.
一名86岁女性在接受双膦酸盐治疗多发性骨髓瘤后出现下颌骨骨坏死，接受了外科清创术和多次拔牙。对坏死骨碎片的组织病理学检查显示为急性骨髓炎，伴有混合菌群，且有形态学上与牙龈内阿米巴相符的微生物。除了口腔刮片和痰液外，在取自子宫、宫颈、颈部淋巴结和肺部的标本中也发现了牙龈内阿米巴。它在头颈部病变中很少见。我们报告了一例在双膦酸盐治疗多发性骨髓瘤后下颌骨急性骨髓炎中出现牙龈内阿米巴的不寻常病例。据我们所知，这是首次报道牙龈内阿米巴与骨髓炎相关的病例。
