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塞来昔布治疗梅毒性全葡萄膜炎后复发性巩膜葡萄膜炎。一例病例报告。

Celecoxib for recurrent sclerouveitis after syphilitic panuveitis. A case report.

作者信息

Suelves Ana M, Martinez-Castillo Sebastián, Salavert Miguel, Díaz-Llopis Manuel

机构信息

Department of Ophthalmology, La Nueva Fé Hospital, Valencia, Spain,

出版信息

J Ophthalmic Inflamm Infect. 2011 Dec;1(4):185-7. doi: 10.1007/s12348-011-0031-0. Epub 2011 Jul 22.

DOI:10.1007/s12348-011-0031-0
PMID:21785853
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3223351/
Abstract

PURPOSE

To report a case of recurrent ocular inflammation after optimal therapy of bilateral syphilitic panuveitis responding to oral celecoxib.

METHODS

A case report was conducted.

RESULTS

A 76-year-old man presented with painful blurry vision in both eyes. Ocular examination disclosed bilateral panuveitis. Serological testing confirmed blood and cerebrospinal fluid syphilitic involvement. After 2 weeks of intravenous penicillin therapy, recurrent episodic sclerouveitis was observed.

CONCLUSION

Ocular inflammation after healing of infectious uveitis is a rare ophthalmic sequela. In an immunocompetent patient, either re-infection or immune uveitis should be evoked. Non-steroidal therapeutic options, as celecoxib, could be a good option of treatment in such immune cases.

摘要

目的

报告1例双侧梅毒性全葡萄膜炎经最佳治疗后复发眼部炎症且口服塞来昔布有效的病例。

方法

进行病例报告。

结果

一名76岁男性出现双眼疼痛性视力模糊。眼部检查发现双侧全葡萄膜炎。血清学检测证实血液和脑脊液有梅毒感染。静脉注射青霉素治疗2周后,观察到复发性发作性巩膜葡萄膜炎。

结论

感染性葡萄膜炎治愈后的眼部炎症是一种罕见的眼科后遗症。在免疫功能正常的患者中,应考虑再次感染或免疫性葡萄膜炎。非甾体类治疗选择,如塞来昔布,可能是此类免疫病例的良好治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65af/3290346/eb736ee0ab2a/12348_2011_31_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65af/3290346/eb736ee0ab2a/12348_2011_31_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65af/3290346/eb736ee0ab2a/12348_2011_31_Fig1_HTML.jpg

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本文引用的文献

1
Syphilitic uveitis: a review of clinical manifestations and treatment outcomes of syphilitic uveitis in human immunodeficiency virus-positive and negative patients.梅毒性葡萄膜炎:人类免疫缺陷病毒阳性和阴性患者梅毒性葡萄膜炎的临床表现和治疗结果的综述。
Clin Exp Ophthalmol. 2010 Jan;38(1):68-74. doi: 10.1111/j.1442-9071.2010.02203.x.
2
Nonsteroidal anti-inflammatory therapy and recurrent acute anterior uveitis.非甾体抗炎治疗与复发性急性前葡萄膜炎。
Ocul Immunol Inflamm. 2010 Apr;18(2):116-20. doi: 10.3109/09273941003587558.
3
Immune responses induced by spirochetal outer membrane lipoproteins and glycolipids.
螺旋体外膜脂蛋白和糖脂诱导的免疫反应。
Immunobiology. 2008;213(3-4):329-40. doi: 10.1016/j.imbio.2007.11.003. Epub 2008 Jan 2.
4
Syphilis: reemergence of an old adversary.梅毒:一种古老对手的再度出现。
Ophthalmology. 2006 Nov;113(11):2074-9. doi: 10.1016/j.ophtha.2006.05.048. Epub 2006 Aug 28.
5
Saving the vision of children with juvenile rheumatoid arthritis-associated uveitis.
JAMA. 1998 Oct 7;280(13):1133-4. doi: 10.1001/jama.280.13.1133.