Human-induced pluripotent stem cells as a source of hepatocyte-like cells: new kids on the block.

作者信息

Busletta C, Novo E, Parola M

机构信息

Department of Experimental Medicine and Oncology, InterUniversity Center for Hepatic Pathophysiology, University of Torino, Corso Raffaello 30, 10125, Turin, Italy.

出版信息

Hepatol Int. 2013 Jun;7(2):299-305. doi: 10.1007/s12072-011-9300-0. Epub 2011 Jul 23.

DOI:10.1007/s12072-011-9300-0

PMID:21785924

Abstract

摘要

相似文献

Human-induced pluripotent stem cells as a source of hepatocyte-like cells: new kids on the block.

Hepatol Int. 2013 Jun;7(2):299-305. doi: 10.1007/s12072-011-9300-0. Epub 2011 Jul 23.

Hepatectomised patient sera promote hepatocyte differentiation of human-induced pluripotent stem cells.肝切除患者血清可促进人诱导多能干细胞的肝细胞分化。

Dig Liver Dis. 2014 Aug;46(8):731-7. doi: 10.1016/j.dld.2014.04.013. Epub 2014 May 29.

Efficient Differentiation of Human Induced Pluripotent Stem Cell (hiPSC) Derived Hepatocyte-Like Cells on hMSCs Feeder.人诱导多能干细胞（hiPSC）来源的类肝细胞在人间充质干细胞饲养层上的高效分化

Int J Hematol Oncol Stem Cell Res. 2014 Oct 1;8(4):20-9.

Differentiation of human foreskin fibroblast-derived induced pluripotent stem cells into hepatocyte-like cells.人包皮成纤维细胞来源的诱导多能干细胞向肝细胞样细胞的分化

Cell Biochem Funct. 2016 Oct;34(7):475-482. doi: 10.1002/cbf.3210. Epub 2016 Aug 29.

Generation of Human Induced Pluripotent Stem Cell-Derived Hepatocyte-Like Cells for Cellular Medicine.用于细胞医学的人诱导多能干细胞衍生的肝细胞样细胞的生成。

Biol Pharm Bull. 2020;43(4):608-615. doi: 10.1248/bpb.b19-00740.

[Establishment of a Method of Hepatocyte Differentiation from Human Pluripotent Stem Cells for Innovative Drug Development].[建立用于创新药物开发的人多能干细胞向肝细胞分化的方法]

Yakugaku Zasshi. 2015;135(10):1141-6. doi: 10.1248/yakushi.15-00194.

Rapid generation of mature hepatocyte-like cells from human induced pluripotent stem cells by an efficient three-step protocol.高效三步法从人诱导多能干细胞中快速生成成熟的肝细胞样细胞。

Hepatology. 2012 Apr;55(4):1193-203. doi: 10.1002/hep.24790. Epub 2012 Mar 1.

Billion-scale production of hepatocyte-like cells from human induced pluripotent stem cells.从人诱导多能干细胞大规模生产类肝细胞

Biochem Biophys Res Commun. 2018 Feb 19;496(4):1269-1275. doi: 10.1016/j.bbrc.2018.01.186. Epub 2018 Feb 1.

Donor-Dependent and Other Nondefined Factors Have Greater Influence on the Hepatic Phenotype Than the Starting Cell Type in Induced Pluripotent Stem Cell Derived Hepatocyte-Like Cells.供体依赖性和其他未定义因素对诱导多能干细胞衍生的类肝细胞中的肝表型的影响大于起始细胞类型。

Stem Cells Transl Med. 2017 May;6(5):1321-1331. doi: 10.1002/sctm.16-0029.

[Generation of Zone-specific Hepatocyte-like Cells from Human Induced Pluripotent Stem Cells for Accurate Prediction of Drug-induced Hepatotoxicity].[从人诱导多能干细胞生成区域特异性肝样细胞以准确预测药物性肝毒性]

Yakugaku Zasshi. 2019;139(12):1509-1512. doi: 10.1248/yakushi.19-00170.

引用本文的文献

Human induced pluripotent stem cells derived hepatocytes: rising promise for disease modeling, drug development and cell therapy.人诱导多能干细胞衍生的肝细胞：疾病建模、药物开发和细胞治疗的新希望。

Protein Cell. 2012 Apr;3(4):246-50. doi: 10.1007/s13238-012-2918-4. Epub 2012 Mar 22.

本文引用的文献

Direct differentiation of hepatic cells from human induced pluripotent stem cells using a limited number of cytokines.使用有限数量的细胞因子将人诱导多能干细胞直接分化为肝细胞。

Hepatol Int. 2011 Dec;5(4):890-8. doi: 10.1007/s12072-011-9251-5. Epub 2011 Feb 6.

The tumorigenicity of human embryonic and induced pluripotent stem cells.人胚胎干细胞和诱导多能干细胞的致瘤性。

Nat Rev Cancer. 2011 Apr;11(4):268-77. doi: 10.1038/nrc3034. Epub 2011 Mar 10.

New approaches in the differentiation of human embryonic stem cells and induced pluripotent stem cells toward hepatocytes.人类胚胎干细胞和诱导多能干细胞向肝细胞分化的新方法。

Stem Cell Rev Rep. 2011 Sep;7(3):748-59. doi: 10.1007/s12015-010-9216-4.

Modeling and therapy of human liver diseases using induced pluripotent stem cells: how far have we come?利用诱导多能干细胞对人类肝脏疾病进行建模和治疗：我们已经走了多远？

Hepatology. 2011 Feb;53(2):708-11. doi: 10.1002/hep.24143.

Stem and progenitor cells in liver regeneration and repair.肝再生和修复中的干细胞和祖细胞。

Cytotherapy. 2011 Feb;13(2):135-44. doi: 10.3109/14653249.2010.545386.

Genetic instability in human induced pluripotent stem cells: classification of causes and possible safeguards.人类诱导多能干细胞中的遗传不稳定性：原因分类及可能的保障措施。

Cell Cycle. 2010 Dec 1;9(23):4603-4. doi: 10.4161/cc.9.23.14094.

Induced pluripotent stem cell-derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice.诱导多能干细胞衍生的肝细胞具有在小鼠中进行肝脏再生所需的功能和增殖能力。

J Clin Invest. 2010 Sep;120(9):3120-6. doi: 10.1172/JCI43267. Epub 2010 Aug 25.

Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells.使用人诱导多能干细胞建立肝脏遗传代谢性疾病模型。

J Clin Invest. 2010 Sep;120(9):3127-36. doi: 10.1172/JCI43122. Epub 2010 Aug 25.

From skin cells to hepatocytes: advances in application of iPS cell technology.从皮肤细胞到肝细胞：iPS 细胞技术应用的进展。

J Clin Invest. 2010 Sep;120(9):3102-5. doi: 10.1172/JCI44422. Epub 2010 Aug 25.

Lab-specific gene expression signatures in pluripotent stem cells.多能干细胞中的特定于实验室的基因表达特征。

Cell Stem Cell. 2010 Aug 6;7(2):258-62. doi: 10.1016/j.stem.2010.06.016.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验