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Human-induced pluripotent stem cells as a source of hepatocyte-like cells: new kids on the block.

作者信息

Busletta C, Novo E, Parola M

机构信息

Department of Experimental Medicine and Oncology, InterUniversity Center for Hepatic Pathophysiology, University of Torino, Corso Raffaello 30, 10125, Turin, Italy.

出版信息

Hepatol Int. 2013 Jun;7(2):299-305. doi: 10.1007/s12072-011-9300-0. Epub 2011 Jul 23.

DOI:10.1007/s12072-011-9300-0
PMID:21785924
Abstract
摘要

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Human induced pluripotent stem cells derived hepatocytes: rising promise for disease modeling, drug development and cell therapy.人诱导多能干细胞衍生的肝细胞：疾病建模、药物开发和细胞治疗的新希望。
Protein Cell. 2012 Apr;3(4):246-50. doi: 10.1007/s13238-012-2918-4. Epub 2012 Mar 22.

本文引用的文献

1
Direct differentiation of hepatic cells from human induced pluripotent stem cells using a limited number of cytokines.使用有限数量的细胞因子将人诱导多能干细胞直接分化为肝细胞。
Hepatol Int. 2011 Dec;5(4):890-8. doi: 10.1007/s12072-011-9251-5. Epub 2011 Feb 6.
2
The tumorigenicity of human embryonic and induced pluripotent stem cells.人胚胎干细胞和诱导多能干细胞的致瘤性。
Nat Rev Cancer. 2011 Apr;11(4):268-77. doi: 10.1038/nrc3034. Epub 2011 Mar 10.
3
New approaches in the differentiation of human embryonic stem cells and induced pluripotent stem cells toward hepatocytes.
人类胚胎干细胞和诱导多能干细胞向肝细胞分化的新方法。
Stem Cell Rev Rep. 2011 Sep;7(3):748-59. doi: 10.1007/s12015-010-9216-4.
4
Modeling and therapy of human liver diseases using induced pluripotent stem cells: how far have we come?利用诱导多能干细胞对人类肝脏疾病进行建模和治疗：我们已经走了多远？
Hepatology. 2011 Feb;53(2):708-11. doi: 10.1002/hep.24143.
5
Stem and progenitor cells in liver regeneration and repair.肝再生和修复中的干细胞和祖细胞。
Cytotherapy. 2011 Feb;13(2):135-44. doi: 10.3109/14653249.2010.545386.
6
Genetic instability in human induced pluripotent stem cells: classification of causes and possible safeguards.人类诱导多能干细胞中的遗传不稳定性：原因分类及可能的保障措施。
Cell Cycle. 2010 Dec 1;9(23):4603-4. doi: 10.4161/cc.9.23.14094.
7
Induced pluripotent stem cell-derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice.诱导多能干细胞衍生的肝细胞具有在小鼠中进行肝脏再生所需的功能和增殖能力。
J Clin Invest. 2010 Sep;120(9):3120-6. doi: 10.1172/JCI43267. Epub 2010 Aug 25.
8
Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells.使用人诱导多能干细胞建立肝脏遗传代谢性疾病模型。
J Clin Invest. 2010 Sep;120(9):3127-36. doi: 10.1172/JCI43122. Epub 2010 Aug 25.
9
From skin cells to hepatocytes: advances in application of iPS cell technology.从皮肤细胞到肝细胞：iPS 细胞技术应用的进展。
J Clin Invest. 2010 Sep;120(9):3102-5. doi: 10.1172/JCI44422. Epub 2010 Aug 25.
10
Lab-specific gene expression signatures in pluripotent stem cells.多能干细胞中的特定于实验室的基因表达特征。
Cell Stem Cell. 2010 Aug 6;7(2):258-62. doi: 10.1016/j.stem.2010.06.016.